| Identification | More | [Name]
N-(2-Acetamido)iminodiacetic acid | [CAS]
26239-55-4 | [Synonyms]
ADA
ADA BUFFER
N-[2-ACETAMIDO]-2-IMINODIACETIC ACID
N-(2-ACETAMIDO)IMINODIACETIC ACID
N-(2-ACETAMINO)-IMINODIACETIC ACID
N-(2-ACETIMIDO)IMINODIACETIC ACID
N-(2-Amino-2-oxoethyl)-N-(carboxymethyl)-glycine
N-(CARBAMOYLMETHYL)IMINODIACETIC
N-(CARBAMOYLMETHYL)IMINODIACETIC ACID
Carbamoylmethylaminodiaceticacid
n-(2-amino-2-oxoethyl)-n-(carboxymethyl)-glycin
N-(2-Acetamide)iminodiacetic acid
N-(2-Acetamido)iminodiacetic acid
N-(Carbamoylmethyl)iminodiacetic acid
ADA, 98%, (N-(2-ACETAMIDO)IMINODIACETIC ACID)
ADA FREE ACID
ADA SIGMAULTRA
N-(2-ACETAMIDO)-IMINODIACETIC ACID 98+% ADA
N-(2-ACETAMIDO)-IMINODIACETIC ACID BIOTECH 99+% ADA
Ada(N-(2-Acetamide)-IminodiaceticAcid)
AdaN-[2-Acetamido]-2-IminodiaceticAcid | [EINECS(EC#)]
247-530-0 | [Molecular Formula]
C6H10N2O5 | [MDL Number]
MFCD00008031 | [Molecular Weight]
190.15 | [MOL File]
26239-55-4.mol |
| Chemical Properties | Back Directory | [Appearance]
white to almost white powder | [Melting point ]
219 °C (dec.)(lit.)
| [Boiling point ]
325.64°C (rough estimate) | [density ]
1.4957 (rough estimate) | [vapor pressure ]
0Pa at 25℃ | [refractive index ]
1.5010 (estimate) | [storage temp. ]
Store at RT. | [solubility ]
1 M NaOH: 0.05 M at 20 °C, clear, colorless
| [form ]
Powder | [color ]
White to almost white | [PH]
1.5-3.0 (25℃, 0.01M in H2O) | [PH Range]
6.0 - 7.2 | [pka]
6.6(at 25℃) | [Water Solubility ]
soluble | [λmax]
λ: 260 nm Amax: 0.20
λ: 280 nm Amax: 0.05 | [Merck ]
14,147 | [BRN ]
1787181 | [InChIKey]
QZTKDVCDBIDYMD-UHFFFAOYSA-N | [LogP]
-3.12 at 20℃ | [CAS DataBase Reference]
26239-55-4(CAS DataBase Reference) | [EPA Substance Registry System]
26239-55-4(EPA Substance) |
| Safety Data | Back Directory | [Safety Statements ]
S24/25:Avoid contact with skin and eyes . | [WGK Germany ]
3
| [TSCA ]
Yes | [HazardClass ]
IRRITANT | [HS Code ]
29241900 |
| Hazard Information | Back Directory | [Description]
ADA is a zwitterionic buffer used in biochemistry and molecular biology. It is one of the Good buffers developed in the 1960′s to provide buffers in the pH range of 6.15 - 8.35 for wide applicability to biochemical studies. The pioneering publication by Good and co-workers describes the synthesis of ADA and its physical properties. The useful range of ADA buffer in aqueous solution is 6.0 - 7.2. | [Chemical Properties]
N-(2-Acetamido)iminodiacetic acid is white to almost white powder
| [Uses]
Biological buffer component with sodium hydroxide and sodium chloride (pH 5.67-7.57, useful pH range 6.4-7.4).Used to prepare immobilized pH gradients. | [Uses]
N-(2-Acetamido)iminodiacetic acid is buffer for biological systems and chelator for metals.
| [Application]
ADA, or N-(2-Acetamido)iminodiacetic acid, can be used to study biological buffers and zwitterionic compounds. ADA has been used in a study to describe the application of scanning capacitively coupled contactless conductivity detection (SC(4)D) for the determination of pH dependant behaviour of two aminopolycarboxylates immobilised onto the surface of a monolithic capillary column.
Biological buffer component with sodium hydroxide and sodium chloride (pH 5.67-7.57, useful pH range 6.4-7.4). Used to prepare immobilized pH gradients. | [Definition]
ChEBI: 2,2'-[(2-amino-2-oxoethyl)imino]diacetic acid is a tricarboxylic acid amide that is a Good's buffer substance, pKa = 6.6 at 20 ℃. It is a dicarboxylic acid, a tricarboxylic acid amide and an ADA. It is functionally related to a nitrilotriacetic acid. It is a conjugate acid of a 2,2'-[(2-amino-2-oxoethyl)imino]diacetate(1-). | [General Description]
ADA is a zwitterionic buffer used in biochemistry and molecular biology. It is one of the Good buffers developed in the 1960′s to provide buffers in the pH range of 6.15 - 8.35 for wide applicability to biochemical studies. The pioneering publication by Good and co-workers describes the synthesis of ADA and its physical properties. The useful range of ADA buffer in aqueous solution is 6.0 - 7.2. | [Flammability and Explosibility]
Notclassified | [Purification Methods]
Dissolve ADA in water, add one equivalent of NaOH solution (to final pH of 8-9), then acidify with HCl to precipitate the free acid. This is filtered off, washed with water and dried in vacuo. [Beilstein 4 IV 2441.] |
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