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ChemicalBook--->CAS DataBase List--->22688-79-5

22688-79-5

22688-79-5 Structure

22688-79-5 Structure
IdentificationBack Directory
[Name]

QUERCETIN-3-O-GLUCURONIDE
[CAS]

22688-79-5
[Synonyms]

CS-149
Mikwelianin
Miquelianin
Quercituron
Querciturone
Miquelianin?, >99%
Quercetin 3-O-ß
Quercetol glucuronide
Quercetol 3-glucuronide
Quercetol 3-O-glucuronide
Quercetin 3-D-glucuronide
Quercetin 3-O-β-D-glucuronide
QUERCETIN-3-O-GLUCURONIDE(RG)
Quercetin 3-glucuronide ,>=99%
Quercetin 3-O-β-D-Glucuronopyranoside
Miquelianin (Quercetin 3-O-glucuronide)
3,3′,4′,5,7-Pentahydroxyflavone 3-glucuronide
QUERCETIN 3-O-GLUCURONIDE; QUERCETIN 3-GLUCURONIDE
Quercetin 3-glucuronide, 98%, from Bupleurum chinense DC.
3',4',5,7-Tetrahydroxyflavon-3-yl β-D-glucopyranosiduronic acid
2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-3-(β-D-glucopyranuronosyloxy)-4H-1-benzopyran-4-one
2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-1-benzopyran-3-yl β-D-Glucopyranosiduronic Acid
b-D-Glucopyranosiduronic acid,2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-1-benzopyran-3-yl
β-D-Glucopyranosiduronic acid, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-1-benzopyran-3-yl
2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-1-benzopyran-3-yl-beta-D-glucopyranosiduronic acid
[Molecular Formula]

C21H18O13
[MDL Number]

MFCD04039814
[MOL File]

22688-79-5.mol
[Molecular Weight]

478.36
Chemical PropertiesBack Directory
[Melting point ]

193~195℃
[Boiling point ]

927.8±65.0 °C(Predicted)
[density ]

1.96±0.1 g/cm3(Predicted)
[storage temp. ]

-20°C
[solubility ]

DMSO (Slightly), Methanol (Slightly)
[form ]

neat
[pka]

2.76±0.70(Predicted)
[color ]

Yellow to Very Dark Yellow
[Stability:]

Very Hygroscopic
[LogP]

2.100 (est)
Safety DataBack Directory
[Safety Statements ]

24/25
[WGK Germany ]

3
Hazard InformationBack Directory
[Description]

Quercetin 3-O-glucuronide is a pharmacologically active flavonol glucuronide isolated from H. perforatum (St. John’s wort) that inhibits the α2c adrenergic receptor (Ki = 4,060 nM in hα2c preparations). Quercetin 3-O-glucuronide (0.6 mg/kg) reduced the time rats spent immobile in the forced swim test, suggesting antidepressant-like properties, when given either acutely or chronically. It also reduced open field stress-induced hyperthermia in mice (at 1.2 mg/kg).
[Chemical Properties]

Yellow Solid
[Uses]

Quercetin 3-O-β-D-Glucuronide is the major metabolite of Quercetin (Q509500).
[Definition]

ChEBI: Miquelianin is a quercetin O-glycoside that consists of quercetin attached to a beta-D-glucuronopyranosyl moiety at position 3 via a glycosidic linkage. Isolated from Salvia and Phaseolus vulgaris, it exhibits antioxidant and antidepressant activities. It has a role as a metabolite, an antioxidant and an antidepressant. It is a beta-D-glucosiduronic acid and a quercetin O-glycoside.
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