| Identification | Back Directory | [Name]
MS4078 | [CAS]
2229036-62-6 | [Synonyms]
MS4078
MS-4078;MS 4078
1-Piperidineacetamide, 4-[4-[[5-chloro-4-[[2-[(1-methylethyl)sulfonyl]phenyl]amino]-2-pyrimidinyl]amino]-2-methyl-5-(1-methylethoxy)phenyl]-N-[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]ethyl]- | [Molecular Formula]
C45H52ClN9O8S | [MOL File]
2229036-62-6.mol | [Molecular Weight]
914.47 |
| Chemical Properties | Back Directory | [density ]
1.377±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : 50 mg/mL (54.68 mM; Need ultrasonic) | [form ]
Solid | [pka]
10.74±0.40(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Description]
MS4078 is a heterobifunctional linker that binds to protein targets and delivers cytotoxic drugs to cancer cells. It has a selective binding affinity for cancer cells and has shown minimal toxicity in pre-clinical studies. | [Uses]
MS4078 is an inhibitor and PROTAC (degrader) of ALK. |
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| Company Name: |
DC Chemicals
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021-58447131 13564518121 |
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http://www.is0513.com/ShowSupplierProductsList927327/0.htm |
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