| Identification | More | [Name]
(S)-(-)-2-Azetidinecarboxylic acid | [CAS]
2133-34-8 | [Synonyms]
(2S)-(-)-AZETIDINE-2-CARBOXYLIC ACID
H-AZE(2)-OH
H-AZE-OH
L-2-AZETIDINECARBOXYLIC ACID
L-AZETIDINE-2-CARBOXYLIC ACID
L-AZETIDINECARBOXYLIC ACID
L-TRIMETHYLENEIMINE-2-CARBOXYLIC ACID
(S)-(-)-2-AZETIDINECARBOXYLIC ACID
(S)-2-AZETIDINE CARBOXYLIC ACID
(S)-(-)-AZETIDINE-2-CARBOXYLIC ACID
(S)-AZETIDINE-2-CARBOXYLIC ACID
(S)-L-2-AZETIDINE CARBOXYLIC ACID
(s)-2-azetidinecarboxylicaci
acidel-azetidine-2-carboxylic
acidel-azetidine-2-carboxylic(french)
l-2-azetidinecarboxylicaci
l-azetidine-2-carboxylicaci
L-AZETIDINE-2-CARBOXYLIC ACID*CRYSTALLIN E
(S)-(-)-2-AZETIDINECARBOXYLIC ACID, 99+%
(S)-(-)-2-Azetidinecarboxylic | [EINECS(EC#)]
218-362-5 | [Molecular Formula]
C4H7NO2 | [MDL Number]
MFCD00005166 | [Molecular Weight]
101.1 | [MOL File]
2133-34-8.mol |
| Chemical Properties | Back Directory | [Appearance]
white to light yellow crystal powder | [Melting point ]
~215 °C (dec.)
| [alpha ]
-125 º (c=1, water 25 ºC) | [Boiling point ]
189.47°C (rough estimate) | [density ]
1.2245 (rough estimate) | [refractive index ]
-122 ° (C=4, H2O) | [storage temp. ]
2-8°C | [solubility ]
Aqueous Base (Slightly), Methanol (Slightly), Water (Slightly) | [form ]
Crystalline Powder or Crystals | [pka]
2.35±0.20(Predicted) | [color ]
White to light beige | [Water Solubility ]
5 g/100 mL | [Usage]
A four-membered ring analog of L-Proline. A useful intermediate in the synthesis of polypeptides | [Merck ]
14,908 | [BRN ]
80678 | [InChIKey]
IADUEWIQBXOCDZ-VKHMYHEASA-N | [CAS DataBase Reference]
2133-34-8(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S24/25:Avoid contact with skin and eyes .
S36:Wear suitable protective clothing .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [WGK Germany ]
3
| [RTECS ]
CM4310500
| [Hazard Note ]
Irritant | [HS Code ]
29339900 | [Hazardous Substances Data]
2133-34-8(Hazardous Substances Data) | [Toxicity]
LD50 scu-mus: 1000 mg/kg 85GDA2 8(1),101,82 |
| Hazard Information | Back Directory | [Chemical Properties]
white to light yellow crystal powder | [Uses]
(S)-(-)-2-Azetidinecarboxylic acid is a four-membered ring analog of L-Proline, It is a useful intermediate in the synthesis of polypeptides,Used in synthesis of abnormally high molecular weight polypeptides.
| [Uses]
Specific proline antagonist. Used in synthesis of abnormally high molecular weight polypeptides. | [Definition]
ChEBI: The (S)-enantiomer of azetidine-2-carboxylic acid. | [General Description]
L-Azetidine-2-carboxylic acid is a non-protein amino acid and teratogenic agent. It is toxic in nature. | [Biochem/physiol Actions]
Azetidine-2-carboxylic acid (AZC) triggers protein aggregation or upregulates the expression of an aggregation-prone mutant protein, upon interference with nascent protein folding. | [Safety Profile]
Moderately toxic by subcutaneousroute. An experimental teratogen. Other experimentalreproductive effects. When heated to decomposition itemits toxic fumes of NOx. | [storage]
Store at -20°C |
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