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ChemicalBook--->CAS DataBase List--->2013-12-9

2013-12-9

2013-12-9 Structure

2013-12-9 Structure
IdentificationMore
[Name]

D(-)-Norvaline
[CAS]

2013-12-9
[Synonyms]

D-2-AMINOPENTANOIC ACID
D(-)-2-AMINOVALERIC ACID
D-2-AMINOVALERIC ACID
D(-)-NORVALINE
D-NORVALINE
H-D-2-AMINOVALERIC ACID
H-D-APE(2)-OH
H-D-NHCH[CH3(CH2)2]-COOH
H-D-NORVALINE
H-D-NVA-OH
(R)-2-AMINO-N-VALERIC ACID
(R)-(-)-2-AMINOPENTANOIC ACID
(R)-2-AMINOPENTANOIC ACID
RARECHEM EM WB 0167
D-NORVALINE SIGMA GRADE
D(-)-NORVALIN 99%
D(-)-NORVALINE 99%
(R)-2-Aminovaleric acid)
H-D-Nva-OH (D-Norvaline
(R)-2-Aminovalericcid
[EINECS(EC#)]

217-936-2
[Molecular Formula]

C5H11NO2
[MDL Number]

MFCD00008097
[Molecular Weight]

117.15
[MOL File]

2013-12-9.mol
Chemical PropertiesBack Directory
[Appearance]

white to off-white crystals or crystalline powder
[Melting point ]

>300 °C(lit.)
[alpha ]

-24 º (c=5, 5N HCl)
[Boiling point ]

222.9±23.0 °C(Predicted)
[density ]

1.2000 (estimate)
[refractive index ]

-25 ° (C=10, 6mol/L HCl)
[storage temp. ]

Store at RT.
[solubility ]

Aqueous Acid (Slightly), Water (Slightly)
[form ]

Solid
[pka]

2.54±0.20(Predicted)
[color ]

White to Off-White
[optical activity]

[α]20/D 24°, c = 10 in 5 M HCl
[Water Solubility ]

SOLUBLE
[Merck ]

14,6716
[BRN ]

1721161
[CAS DataBase Reference]

2013-12-9(CAS DataBase Reference)
Safety DataBack Directory
[Hazard Codes ]

Xn
[Risk Statements ]

R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
R36/37/38:Irritating to eyes, respiratory system and skin .
[Safety Statements ]

S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes .
S37/39:Wear suitable gloves and eye/face protection .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
[WGK Germany ]

3
[HS Code ]

29224919
Hazard InformationBack Directory
[Chemical Properties]

white to off-white crystals or crystalline powder
[Uses]

D-Norvaline is used as a catalyst in the enantioselective α-bromination of carbonyl and 1,3-dicarbonyl compounds. D-Norvaline is also incorporated into jadomycins (a group of compounds that are widely used as antibiotics), ultimately producing compounds that have potential antiproliferative/anti-cancer properties.
[Definition]

ChEBI: D-2-aminopentanoic acid is a 2-aminopentanoic acid that has R-configuration. It has a role as an EC 6.1.1.4 (leucine--tRNA ligase) inhibitor. It is a D-alpha-amino acid and a 2-aminopentanoic acid. It is an enantiomer of a L-2-aminopentanoic acid.
[reaction suitability]

reaction type: solution phase peptide synthesis
Spectrum DetailBack Directory
[Spectrum Detail]

D(-)-Norvaline(2013-12-9)1HNMR
D(-)-Norvaline(2013-12-9)13CNMR
D(-)-Norvaline(2013-12-9)IR1
D(-)-Norvaline(2013-12-9)IR2
D(-)-Norvaline(2013-12-9)Raman
Well-known Reagent Company Product InformationBack Directory
[Acros Organics]

D(-)-Norvaline, 99%(2013-12-9)
[Alfa Aesar]

D-Norvaline, 99%(2013-12-9)
[Sigma Aldrich]

2013-12-9(sigmaaldrich)
[TCI AMERICA]

D-Norvaline,>99.0%(T)(2013-12-9)
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