| Identification | More | [Name]
Methyl 2-aminonicotinate | [CAS]
14667-47-1 | [Synonyms]
2-AMINO-NICOTINIC ACID METHYL ESTER
METHYL 2-AMINONICOTINATE
RARECHEM AL BF 1234
Methyl 2-aminopyridine-3-carboxylate
2-METHYL-4-(TRIFLUOROMETHYL)-5-AMINOTHIAZOLE
2-Amino-3-pyridinecarboxylic acid methyl ester
2-Aminopyridine-3-carboxylic acid methyl ester | [EINECS(EC#)]
681-092-5 | [Molecular Formula]
C7H8N2O2 | [MDL Number]
MFCD00128872 | [Molecular Weight]
152.15 | [MOL File]
14667-47-1.mol |
| Chemical Properties | Back Directory | [Melting point ]
82-86 °C | [Boiling point ]
251.3±20.0 °C(Predicted) | [density ]
1.238±0.06 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Sealed in dry,Room Temperature | [solubility ]
soluble in Methanol | [form ]
powder to crystal | [pka]
4.71±0.36(Predicted) | [color ]
White to Almost white | [InChI]
InChI=1S/C7H8N2O2/c1-11-7(10)5-3-2-4-9-6(5)8/h2-4H,1H3,(H2,8,9) | [InChIKey]
NZZDEODTCXHCRS-UHFFFAOYSA-N | [SMILES]
C1(N)=NC=CC=C1C(OC)=O | [CAS DataBase Reference]
14667-47-1(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S22:Do not breathe dust .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection . | [WGK Germany ]
2 | [HazardClass ]
IRRITANT | [HS Code ]
2933399990 |
| Hazard Information | Back Directory | [Chemical Properties]
Off white powder | [Uses]
Methyl 2-Aminonicotinate is used to prepare 2-{4-[(3S)-Piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide (MK-4827)as a novel oral poly(ADP-ribose)polymerase (PARP) inhibitor efficacious in BRCA-1 and -2 mutant tumors. It is also used to synthesize quinazolinone/quinazoline thione derivatives as phosphodiesterase 7 inhibitors. |
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