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ChemicalBook--->CAS DataBase List--->1405-53-4

1405-53-4

1405-53-4 Structure

1405-53-4 Structure
IdentificationMore
[Name]

Tylosin phosphate
[CAS]

1405-53-4
[Synonyms]

2-[12-[5-(4,5-DIHYDROXY-4,6-DIMETHYL-OXAN-2-YL)OXY-4-DIMETHYLAMINO-3-HYDROXY-6-METHYL-OXAN-2-YL]OXY-2-ETHYL-14-HYDROXY-3-[(5-HYDROXY-3,4-DIMETHOXY-6-METHYL-OXAN-2-YL)OXYMETHYL]-5,9,13-TRIMETHYL-8,16-DIOXO-1-OXACYCLOHEXADECA-4,6-DIEN-11-YL]ACETALDEHYDE, PHOSPHORIC ACID
TYLAN
TYLOSIN PHOSPHATE
Tylosin, phosphate (salt)
TYLOSIN PHOSPHATE PREMIX 25%
TylosinPhosphate80%
Farmazin TB
2-[(4R,5S,6S,7R,9R,11E,13E,15R,16R)-6-[(2R,3R,4R,5S,6R)-5-[(2S,4R,5S,6S)-4,5-Dihydroxy-4,6-dimethyloxan-2-yl]oxy-4-dimethylamino-3-hydroxy-6-methyloxan-2-yl]oxy-16-ethyl-4-hydroxy-15-[[(2R,3R,4R,5R,6R)-5-hydroxy-3,4-dimethoxy-6-methyloxan-2-yl]oxymethyl]-5,9,13-trimethyl-2,10-dioxo-1-oxacyclohexadeca-11,13-dien-7-yl]acetaldehyde phosphate
Tyrosine [antibiotic]/phosphoric acid,(1:x)
Pharmasine TB
Tylan 10 premix
Tylan 40 premix
[EINECS(EC#)]

215-779-4
[Molecular Formula]

C46H80NO21P
[MDL Number]

MFCD06795692
[Molecular Weight]

1014.1
[MOL File]

1405-53-4.mol
Chemical PropertiesBack Directory
[Melting point ]

>128°C (dec.)
[storage temp. ]

2-8°C
[solubility ]

Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
[form ]

neat
[color ]

Pale Yellow
[Stability:]

Hygroscopic
[InChIKey]

NBOODGNJLRRJNA-DRHKFUGVNA-N
[CAS DataBase Reference]

1405-53-4(CAS DataBase Reference)
Safety DataBack Directory
[WGK Germany ]

2
[RTECS ]

YP0625000
[Toxicity]

Tylosin base and its salts were shown to be of low acute oral toxicity with LD50 values in excess 5000 mg/kg bw in the rat and mouse and greater than 800 mg/kg bw in the dog.
Hazard InformationBack Directory
[Chemical Properties]

Tylosin phosphate (TS) is a light yellow to yellow liquid substance with a characteristic odor.
Tylosin phosphate
Tylosin phosphate has an antibacterial effect mainly on Gram-positive bacteria and partly on Gramnegative bacteria and mycoplasma, and has a growth-promoting effect on pigs.
[Uses]

Tylosin phosphate is a pure-grade antibiotic that was designated as a feed additive as of July 24, 1976. It is used for prevention and control of chronic respiratory disease (CRD) in replacement pullets, broilers, increasing bodyweight and improvement of feed conversion rate in broilers, increasing egg production.
[General Description]

Tylosin phosphate is an antibacterial agent employed against mycoplasma organisms. It is only used in veterinary field and effective basically against gram positive bacteria, but also has efficacy against some spirochetes and gram negatives (except coliforms). Tylosin phosphate, marketed as Tylan 40 or Tylan 100 Type A medicated article, is approved for use in beef cattle to reduce the incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes.
[Mechanism of action]

Tylosin phosphate is an antibiotic of macrolide group which is produced by fermentation of a certain fungus. This antibiotic prevents protein synthesis by ribosomes and thus prevents bacterial growth, resulting in their death. Special mechanism of action of macrolides, besides stopping rapid growth of microorganisms prevents buildup of bacterial resistance.
[storage]

Store at -20°C
Spectrum DetailBack Directory
[Spectrum Detail]

Tylosin phosphate(1405-53-4)MS
Well-known Reagent Company Product InformationBack Directory
[Sigma Aldrich]

1405-53-4(sigmaaldrich)
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