| Identification | Back Directory | [Name]
Chloro[(tri-tert-butylphosphine)-2-(2-aMinobiphenyl)]palladiuM(II) | [CAS]
1375325-71-5 | [Synonyms]
P(tBu)3 Pd G2
tBu3PPdG2 catalyst
Chloro[(tri-t-butylphosphine)-2-(2-aminobiphenyl)]palladium(II)
Chloro[(tri-tert-butylphosphine)-2-(2-aMinobiphenyl)]palladiuM(II)
Chloro(tri-t-butylphosphine)(2'-amino-1,1'-biphenyl-2-yl)palladium(II)
Chloro[(tri-tert-butylphosphine)-2-(2-aminobiphenyl)]palladium(II)
Chloro[(tri-tert-butylphosphine)-2'-amino[1,1'-biphenyl]-2-yl]palladium(II)
Chloro(tri-t-butylphosphine)(2'-amino-1,1'-biphenyl-2-yl)palladium(II), min. 98% | [Molecular Formula]
C24H37ClNPPd+2 | [MDL Number]
MFCD21608496 | [MOL File]
1375325-71-5.mol | [Molecular Weight]
512.404 |
| Questions And Answer | Back Directory | [Physical Form]
Light yellow to Amber to Dark green powder to crystal. | [Reaction]
Catalyst for the Suzuki Coupling of brominated 2,1-borazaronaphthalenes and potassium organotrifluoroborates.
|
| Chemical Properties | Back Directory | [Melting point ]
158-160°C | [form ]
Powder | [color ]
yellow | [InChI]
InChI=1S/C12H9N.C12H27P.ClH.Pd/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10;1-10(2,3)13(11(4,5)6)12(7,8)9;;/h1-6,8-9,13H;1-9H3;1H;/q-2;;;+2 | [InChIKey]
CCFGXRYKSYUWKT-UHFFFAOYSA-N | [SMILES]
P([Pd+2]1(NC2=CC=CC=C2C2=CC=CC=[C-]12)[Cl-])(C(C)(C)C)(C(C)(C)C)C(C)(C)C |
| Hazard Information | Back Directory | [Uses]
P(t-Bu)3 Pd G2 (Chloro[(tri-tert-butylphosphine)-2-(2-aminobiphenyl)] palladium(II), Pd/P(t-Bu)3) may be used as catalyst in the following studies:
- Synthesis of sterically hindered biaryls (tetra-ortho-substituted), via cross-coupling reactions of aryl chlorides.
- Stille cross-couplings reactions of aryl chloride.
- Synthesis of chloropeptin I, via Stille cross-coupling reaction.
- Heck reaction.
- Negishi cross-coupling reactions.
| [Application]
Catalyst for the Suzuki Coupling of brominated 2,1-borazaronaphthalenes and potassium organotrifluoroborates. | [General Description]
P(t-Bu)3 Pd G2 (Chloro[(tri-tert-butylphosphine)-2-(2-aminobiphenyl)] palladium(II)) is a second generation (G2) precatalyst containing a biphenyl-based ligand. Product participates in various palladium catalyzed cross-coupling reactions, C-C, C-N and C-O bond formation reactions, and Suzuki-Miyaura coupling reactions. It generates active Pd catalyst at room temperature in the presence of weak phosphate or carbonate bases. It has been proposed as an active catalyst for use in Stille reactions of aryl halides (bromides and chlorides). |
|
|