| Identification | More | [Name]
Fmoc-L-tert-leucine | [CAS]
132684-60-7 | [Synonyms]
FMOC-ALPHA-T-BUTYLGLYCINE
FMOC-ALPHA-T-BUTYL-GLY-OH
FMOC-L-ALPHA-T-BUTYLGLYCINE
FMOC-L-T-BUTYLGLYCINE
FMOC-L-TERT-LEUCINE
FMOC-L-TLE-OH
FMOC-TBU-GLYCINE
FMOC-TBU-GLY-OH
FMOC-TLE-OH
N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-L-ALPHA-T-BUTYLGLYCINE
N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-L-TERT-LEUCINE
N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-L-T-LEUCINE
N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-(S)-2-AMINO-3,3-DIMETHYL-BUTYRIC ACID
N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-L-TERT-BUTYL-GLYCINE
N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-L-T-LEUCINE
N-ALPHA-FMOC-L-ALPHA-T-BUTYL-GLYCINE
N-ALPHA-FMOC-L-T-BUTYLGLYCINE
N-ALPHA-FMOC-L-T-LEUCINE
N-ALPHA-T-FMOC-L-ALPHA-T-BUTYL-GLYCINE
N-ALPHA-T-FMOC-L-T-LEUCINE | [Molecular Formula]
C21H23NO4 | [MDL Number]
MFCD00065649 | [Molecular Weight]
353.41 | [MOL File]
132684-60-7.mol |
| Chemical Properties | Back Directory | [Melting point ]
124-127 °C | [Boiling point ]
554.1±33.0 °C(Predicted) | [density ]
1.209±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C
| [solubility ]
≥ 35.3mg/mL in DMSO, ≥ 49.6 mg/mL in EtOH | [form ]
powder to crystal | [pka]
3.92±0.10(Predicted) | [color ]
White to Light yellow | [BRN ]
6662856 | [CAS DataBase Reference]
132684-60-7(CAS DataBase Reference) |
| Safety Data | Back Directory | [Safety Statements ]
S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes . | [WGK Germany ]
3
| [HazardClass ]
IRRITANT | [HS Code ]
29242990 |
| Hazard Information | Back Directory | [Chemical Properties]
solid | [Uses]
Fmoc-Tle-OH is a versatile reactant used in the discovery of potent antagonists of antiapoptotic protein X-linked inhibitor of apoptosis (XIAP) for treatment of cancer. It is also used as reactant in the preparation of phosphino dipeptide derivatices as ligand in copper-phosphine catalyst for asymmetric conjugate addition of alkylzinc reagents to unsaturated ketones. |
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