| Identification | More | [Name]
Triisopropylsilyl chloride | [CAS]
13154-24-0 | [Synonyms]
CHLOROTRIISOPROPYLSILANE
SILANE IP3
TIPSCI
TIPSCL
TRIISOPROPYLCHLOROSILANE
TRIISOPROPYLSILYL CHLORIDE
tris-Isopropylchlorosilane
Triisopropylsilyl Clorid
Triisopropylchlorosilane (TIPSCl)
CHLOROTRIISOPROPYLSILANE, WACKER QUALITY
TRIISOPROPYLSILYL CHLORIDE, TECH., 90%
TRIISOPROPYLCHLOROSILANE 98%
TRIISOPROPYLCHLOROSILANE, REDISTILLED
Triisoprpylchlorosilane
Silane, chlorotris(1-methylethyl)-
Tris(isopropylsilyl) chloride
Chlorotriisopropylsilane, 97+%
Triisopropylsilyl chloride Chlorotriisopropylsilane
TIPSCl, Triisopropylchlorosilane, Triisopropylsilyl chloride
Silane IP3, TIPSCl, Triisopropylchlorosilane, Triisopropylsilyl chloride | [EINECS(EC#)]
603-492-0 | [Molecular Formula]
C9H21ClSi | [MDL Number]
MFCD00009656 | [Molecular Weight]
192.8 | [MOL File]
13154-24-0.mol |
| Chemical Properties | Back Directory | [Appearance]
Colorless clear liquid | [Boiling point ]
198 °C739 mm Hg(lit.)
| [density ]
0.901 g/mL at 25 °C(lit.)
| [vapor pressure ]
1.16 mm Hg ( 20 °C)
| [refractive index ]
n20/D 1.452(lit.)
| [Fp ]
145 °F
| [storage temp. ]
Inert atmosphere,2-8°C | [solubility ]
Sol THF, DMF, CH2Cl2. | [form ]
liquid | [color ]
colorless | [Specific Gravity]
0.903 | [Water Solubility ]
Miscible with water. | [Hydrolytic Sensitivity]
8: reacts rapidly with moisture, water, protic solvents | [Sensitive ]
Moisture Sensitive | [Detection Methods]
GC,NMR | [BRN ]
1737446 | [InChIKey]
KQIADDMXRMTWHZ-UHFFFAOYSA-N | [CAS DataBase Reference]
13154-24-0(CAS DataBase Reference) | [NIST Chemistry Reference]
Triisopropylsilyl chloride(13154-24-0) | [Storage Precautions]
Moisture sensitive |
| Safety Data | Back Directory | [Hazard Codes ]
C | [Risk Statements ]
R34:Causes burns. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S27:Take off immediately all contaminated clothing .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S36/39:Wear suitable protective clothing and eye/face protection . | [RIDADR ]
UN 2987 8/PG 2
| [WGK Germany ]
3
| [F ]
10-21 | [Hazard Note ]
Corrosive | [TSCA ]
No | [HazardClass ]
8 | [PackingGroup ]
II | [HS Code ]
29319099 |
| Hazard Information | Back Directory | [Description]
Triisopropyl chlorosilane is an important sterically hindered organosilicon protective agent, which is mainly used to protect various types of hydroxyl groups, especially in polyfunctional hydroxyl compounds, which can be selectively protected and deprotected. It is very important to synthesize nucleosides, nucleotides and carbohydrates. Triisopropylchlorosilane is a good hydroxyl protecting agent, and its silanization reaction is carried out in a slight excess of imidazole solution. The acid hydrolytic stability of the protected intermediate is between TBDMS and TBDPS and the alkaline hydrolytic stability is higher than the former two. | [Chemical Properties]
Triisopropylsilyl chloride is colorless clear liquid
| [Physical properties]
bp 198 °C/739 mmHg; d 0.901 g cm?3. | [Application]
Triisopropyl chlorosilane is mainly used as a basic intermediate in the synthesis of organic silicon materials and a blocking agent for silicone oil or silicone rubber. These triisopropylchlorosilanes can be used as raw materials for preparing functional silanes or silane coupling agents. In the reaction with organometallic compounds, the chlorine atoms of triisopropylchlorosilane are replaced by corresponding organic groups to form organochlorosilanes or organofunctional silanes.
Triisopropyl chlorosilane is mainly used in the production of aminosilane and methacryloxysilane, and can also be used as a rubber processing additive to couple inorganic fillers in various halogenated rubbers, such as neoprene rubber, chlorobutyl rubber , chlorosulfonated polyethylene and other halogenated rubbers. The existence of triisopropylchlorosilane can greatly improve various physical and mechanical properties of composites. Triisopropylchlorosilane can also be used to prepare antifungal and deodorant finishes with special bactericidal, deodorant, antistatic and surface-active properties. | [Preparation]
There are two main methods for synthesizing triisopropyl chlorosilane. One is to use triisopropyl silane as a raw material, and hydrochloric acid and other reagents are used to chlorinate the hydrogen on the silicon. Another method uses silicon tetrachloride as raw material, and reacts with isopropyl lithium to obtain triisopropyl chlorosilane. |
| Questions And Answer | Back Directory | [Uses]
Triisopropyl chlorosilane has found new applications as a blocking group. It has been utilized to prepare blocked derivatives of hydroxy compounds. Derivatization of substrates is accomplished efficiently in DMF containing a slight molar excess of imidazole. Blocked intermediates exhibited acidic hydrolytic stability intermediate between that of a Tert-butyldimethylchlorosilane and Tert-butyldiphenyl chlorosilane derivatives. Greater stability was obtained with Triisopropylchlorosilane under basic conditions.
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