| Identification | More | [Name]
Ferrocenecarboxylic acid | [CAS]
1271-42-7 | [Synonyms]
(CARBOXYCYCLOPENTADIENYL)-CYCLOPENTADIENYLIRON
CARBOXYFERROCENE
FERROCENE, CARBOXY-
FERROCENECARBOXYLIC ACID
FERROCENE MONOCARBOXYLIC ACID
Ferroncene Monocarboxylic Acid
FERROENECARBOXYLIC ACID
Ferocene monocarboxylic acid
Ferrocenemonocarboxylicacid,min.97%
FERROCENECARBOXYLIC ACID (controlled chemical)
FEPRAZONE
Ferrocene monocarboxylic acid, min. 97% | [EINECS(EC#)]
215-040-6 | [Molecular Formula]
C11H10FeO2 10* | [MDL Number]
MFCD00001430 | [Molecular Weight]
230.04 | [MOL File]
1271-42-7.mol |
| Chemical Properties | Back Directory | [Appearance]
dark brown powder | [Melting point ]
210 °C (dec.)(lit.)
| [storage temp. ]
Flammables area | [solubility ]
Chloroform (Sparingly), DMSO (Slightly), Methanol (Slightly) | [form ]
crystal | [color ]
yellow | [Stability:]
Stable. Incompatible with strong oxidizing agents. | [Water Solubility ]
Insoluble in water. | [Exposure limits]
ACGIH: TWA 1 mg/m3
NIOSH: TWA 1 mg/m3 | [InChI]
InChI=1S/C6H5O2.C5H5.Fe/c7-6(8)5-3-1-2-4-5;1-2-4-5-3-1;/h1-4H,(H,7,8);1-5H; | [InChIKey]
VUJLGCHOGQEAED-UHFFFAOYSA-N | [SMILES]
[C]1(C(=O)O)[CH][CH][CH][CH]1.[CH]1[CH][CH][CH][CH]1.[Fe] |^1:0,4,5,6,7,8,9,10,11,12| | [CAS DataBase Reference]
1271-42-7(CAS DataBase Reference) | [NIST Chemistry Reference]
Ferrocene carboxylic acid(1271-42-7) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin .
R22:Harmful if swallowed. | [Safety Statements ]
S37/39:Wear suitable gloves and eye/face protection .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [WGK Germany ]
3
| [HS Code ]
29319090 |
| Hazard Information | Back Directory | [Description]
Ferrocenecarboxylic acid is a metal-organic compound characterized by connecting two ferrocene molecules through a carboxy ligand. Notably, ferrocene is a stable yet highly reactive metal-organic compound that has been extensively researched due to its potential applications in catalysis, materials science, and medicine. It serves as a catalyst in catalysis, facilitating the synthesis of diverse compounds through polymerization, oxidation, and reduction reactions. In materials science, it acts as a fundamental molecular building block for synthesizing polymers and nanomaterials. Although the precise mechanism of action of Ferrocenecarboxylic acid remains fully elucidated, it is believed that the carboxy ligand binds to the ferrocene molecules, forming a stable complex. This complex, in turn, engages with other molecules, including proteins, to facilitate various reactions[1-2].
| [Chemical Properties]
dark brown powder | [Uses]
Ferrocenecarboxylic acid is used to esterify complex mixtures of phenols and alcohols for analysis by GCMS. | [Purification Methods]
It crystallises as yellow crystals from pet ether (m 225-230odec), CHCl3 (m 208.5odec), toluene/pet ether (m 195-205odec), or aqueous ethanol. [Matsue et al. J Am Chem Soc 107 3411 1985.] The acid chloride m 49o crystallises from pentane, and has max at 458nm [Lau & Hart J Org Chem 24 280 1959]. The methyl ester crystallises from aqueous MeOH with m 70-71o. The anhydride has m 143-145o when recrystallised from pet ether [Acton & Silverstein J Org Chem 24 1487 1959]. The amide has m 168-170o when crystallised from CHCl3/Et2O or m 167-169o when crystallised from *C6H6/MeOH. [Arimoto & Haven J Am Chem Soc 77 6295 1955, Benkeser et al. J Am Chem Soc 76 4025 1954.] [Beilstein 16 IV 1807.] | [References]
[1] C. Pess?a, L. Kubota, Y. Gushikem. “Ferrocenecarboxylic acid adsorbed on Nb2O5 film grafted on a SiO2 surface: NADH oxidation study.” Electrochimica Acta 46 1 (2001): 2499–2505.
[2] H. Tsukube, S. Shinoda, H. Fukui. “Synergistic binding and chirality sensing of unprotected amino acids with ferrocenecarboxylic acid–crown ether conjugate.” Tetrahedron Letters 42 1 (2001): 7583–7585.
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