| Identification | More | [Name]
L-2-Aminoadipic acid | [CAS]
1118-90-7 | [Synonyms]
2-AMINO-HEXANEDIOIC ACID
AAD
ALPHA-AMINOHEXANDIOIC ACID
AMINOADIPIC ACID, L-2-
H-2-AAD-OH
H-AAD-OH
HEXANEDIOIC ACID, 2-AMINO-, (2S)-
H-HOMOGLU-OH
H-L-HOGLU-OH
HOMOGLUTAMIC ACID
L-2-AMINOADIPIC ACID
L-2-AMINOHEXANEDIOIC ACID
L-A-AMINOADIPIC ACID
L-ALPHA-AMINOADIPIC ACID
L-ALPHA-AMINOHEXANEDIOIC ACID
L-HOMOGLUTAMIC ACID
NH2-CH[(CH2)3-COOH]-COOH
(S)-2-AMINOHEXANEDIOIC ACID
L-aminohexanoic diacid
(S)-2-Aminohexanedioic acid L-Homoglutamic acid Aad | [EINECS(EC#)]
601-134-8 | [Molecular Formula]
C6H11NO4 | [MDL Number]
MFCD00002636 | [Molecular Weight]
161.16 | [MOL File]
1118-90-7.mol |
| Chemical Properties | Back Directory | [Appearance]
WHITE SOLID | [Melting point ]
203-205 °C (dec.)(lit.) | [alpha ]
22 º (c=2, 5 N HCl 25 ºC) | [Boiling point ]
287.44°C (rough estimate) | [density ]
1.3482 (rough estimate) | [refractive index ]
1.4230 (estimate) | [storage temp. ]
Store at RT. | [solubility ]
1N HCl: 10 mg/ml; PBS (pH 7.2): 0.5 mg/ml | [form ]
Solid | [pka]
2.49±0.24(Predicted) | [color ]
White | [Water Solubility ]
Soluble in 1N HCl (50 mg/ml) and water (slightly). | [BRN ]
1724348 | [InChIKey]
OYIFNHCXNCRBQI-BYPYZUCNSA-N | [CAS DataBase Reference]
1118-90-7(CAS DataBase Reference) |
| Safety Data | Back Directory | [Safety Statements ]
S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes . | [WGK Germany ]
3
| [HS Code ]
29224999 |
| Hazard Information | Back Directory | [Chemical Properties]
WHITE SOLID | [Uses]
An inhibitor of ischemic glutamate release | [Uses]
L-2-Aminoadipic acid is an important raw material and intermediate used in organic synthesis, pharmaceuticals and agrochemicals. | [Definition]
ChEBI: The L-enantiomer of 2-aminoadipic acid. | [General Description]
L-2-Aminoadipic acid/α-aminoadipate is a gliotoxin and is a structural analog of glutamine. It is generated by the catabolism of lysine saccharopine (SAC)/pipecolic acid (PIP) pathways. | [Biochem/physiol Actions]
L-2-Aminoadipic acid inhibits glutamine synthetase and γ-glutamylcysteine synthetase. It modulates glucose metabolism and is present in higher levels in diabetic patients. L-2-Aminoadipic acid plays a key role in suppressing autophagy in C2C12 myotubes. |
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