| Identification | More | [Name]
Ethyl (triphenylphosphoranylidene)acetate | [CAS]
1099-45-2 | [Synonyms]
AURORA KA-1176
(CARBETHOXYMETHYLENE)TRIPHENYLPHOSPHORANE
(CARBOETHOXYMETHYLENE)TRIPHENYLPHOSPHORANE
EMY
(ETHOXYCARBONYLMETHYLENE)TRIPHENYLPHOSPHORANE
ETHYL (TRIPHENYLPHOSPHORANYLIDEN)ACETATE
ETHYL (TRIPHENYLPHOSPHORANYLIDENE)ACETATE
ETHYL (TRIPHENYLPHOSPHORYLIDENE)ACETATE
(TRIPHENYLPHOSPHORANYLIDENE)ACETIC ACID ETHYL ESTER
(triphenylphosphoranylidene)-aceticaciethylester
(Carbethoxymethylene)triphenylphosphorane,free of carbomethoxymethylene-analogue
(Carbethoxymethylene)triphenylphosphorane~(Carboethoxymethylene)triphenylphosphorane~Ethyl (triphenylphosphoranylidene)acetate
(ETHOXYCARBONYLMETHYLENE)TRIPHENYLPHOSPHORANE, 98+%
Carbethoxymethylene triphenylphosphorane, 98+%
CEMTPP
ACETICACID,(TRIPHENYLPHOSPHORANYLIDENE)-,ETHYLESTER
(TRIPHENYL-LAMBDA*5*-PHOSPHANYLIDENE)-ACETIC ACID ETHYL ESTER
(CARBETHOXYMETHYLENE)-TRIPHENY PHOSPHOSPHORANE
(2-Ethoxy-2-oxoethylidene)triphenylphosphorane
2-(Triphenylphosphoranylidene)acetic Acid Ethyl Ester | [EINECS(EC#)]
214-151-7 | [Molecular Formula]
C22H21O2P | [MDL Number]
MFCD00009183 | [Molecular Weight]
348.37 | [MOL File]
1099-45-2.mol |
| Chemical Properties | Back Directory | [Appearance]
Off-White Solid | [Melting point ]
128-130 °C (lit.) | [Boiling point ]
490.4±28.0 °C(Predicted) | [density ]
1.086 g/cm3 | [storage temp. ]
2-8°C
| [solubility ]
Chloroform, THF | [form ]
Powder | [color ]
White to light yellow | [Water Solubility ]
Insoluble | [Sensitive ]
Air Sensitive | [Usage]
A common Wittig reagent. A cholinesterase inhibitor. | [BRN ]
754639 | [InChIKey]
IIHPVYJPDKJYOU-UHFFFAOYSA-N | [CAS DataBase Reference]
1099-45-2(CAS DataBase Reference) | [EPA Substance Registry System]
1099-45-2(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
T,Xi,Xn | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin .
R25:Toxic if swallowed.
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed . | [Safety Statements ]
S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S37/39:Wear suitable gloves and eye/face protection .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [RIDADR ]
UN2811 | [WGK Germany ]
3
| [Hazard Note ]
Irritant | [TSCA ]
Yes | [HS Code ]
29310095 |
| Questions And Answer | Back Directory | [Description]
Ethyl (triphenylphosphoranylidene)acetate is a common Wittig reagent in organic synthesis as well as a cholinesterase inhibitor that inhibits both AChE and BChE. It is used in the preparation of indole from o-nitrobenzaldehydes, coumarins from o-hydroxy acetophenone.
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| Hazard Information | Back Directory | [Chemical Properties]
Off-White Solid | [Uses]
A common Wittig reagent. A cholinesterase inhibitor. | [Uses]
It acts as an inhibitor and inhibits the activity of cholinesterase. | [Purification Methods]
Crystallise it by dissolving it in AcOH and adding pet ether (b 40-50o) to give colourless plates. UV (A 1% ): 222nm (865) and 268nm (116) [Isler et max 1mm al. Helv Chim Acta 40 1242 1957]. [Beilstein 16 IV 977.] |
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