ChemicalBook CAS DataBase List TRIISOPROPYL PHOSPHATE

TRIISOPROPYL PHOSPHATE synthesis

15synthesis methods

Product Name:TRIISOPROPYL PHOSPHATE
CAS Number:513-02-0
Molecular formula:C9H21O4P
Molecular Weight:224.23

67-63-0 Synthesis

67-63-0
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$16.00/25ML

513-02-0
37 suppliers
$44.79/100g

Yield: 97%

Reaction Conditions:

with trichlorophosphate in acetone at 10 - 30; under 10 Torr; for 4 h;

Steps:

10 Eaxmple 10
In a 2L to of the three-port flask 480.8g, 8mol isopropanol, then adding acetone 92.9g, 3 . 2mol, after stirring and mixing cooling to 10 °C the following, stirring next adds by drops 245.33g, 1 . 6mol phosphorus oxychloride, control the mixture temperature is not higher than 10 °C.50 minutes after the dropping. Stirring 10 minutes, under the condition of vacuum heating to 30 degrees, the vacuum degree 10mmHg, reaction 3h, the end of the reaction, adding containing 20.5g isopropanol the sodium is mellow solution, stirring for one hour, water after cooling, dissolve, produce sodium chloride, separating, collecting the organic phase, the organic phase washed to neutral, moisture is removed by reduced pressure distillation and low-boiling isopropanol and monoethyl ether, the purity is not less than 96% of the phosphoric acid product three c the ester is thick 358.8g, the fractionating column, pressure reducing fractionated 348.0g triisopropyl phosphate, yield 97.0%, purity ≥ 99.5%.

References:

Yunnan Yuntianhua Chemical Phosphorus Industry Research and Technology Co., Ltd.;He, Jinjie;Cneg, Bo;Ma, Hang;Wan, Banglong;Wang, Yan CN105859770, 2016, A Location in patent:Paragraph 0048; 0049