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ChemicalBook CAS DataBase List tert-butyl 3,5-dibroMobenzoate
422569-46-8

tert-butyl 3,5-dibroMobenzoate synthesis

3synthesis methods
626-39-1 Synthesis
1,3,5-Tribromobenzene

626-39-1
470 suppliers
$5.00/5g

24424-99-5 Synthesis
Di-tert-butyl dicarbonate

24424-99-5
840 suppliers
$13.50/25G

tert-butyl 3,5-dibroMobenzoate

422569-46-8
15 suppliers
inquiry

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Yield:422569-46-8 97%

Reaction Conditions:

Stage #1: 1,3,5-trisbromobenzenewith n-butyllithium;butyl magnesium bromide in tetrahydrofuran;hexane;toluene at -10;
Stage #2: di-tert-butyl dicarbonate in tetrahydrofuran;hexane;toluene at -10;
Stage #3: with citric acid in tetrahydrofuran;hexane;toluene;Further stages.;

References:

Li, Hongmei;Balsells, Jaume [Tetrahedron Letters,2008,vol. 49,# 12,p. 2034 - 2037]

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