Phenyl tribromomethyl sulfone synthesis
- Product Name:Phenyl tribromomethyl sulfone
- CAS Number:17025-47-7
- Molecular formula:C7H5Br3O2S
- Molecular Weight:392.89
3112-85-4
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$15.00/5g
17025-47-7
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$6.00/1g
Yield:17025-47-7 72%
Reaction Conditions:
with bromine;sodium hydroxide at 75; for 5 h;
Steps:
Sulfone bromination with sodium hypobromite-general procedure
General procedure: To a solution of NaOH (15% w/w, 8 mL) cooled to 5 °C, Br2 (0.4 mL, 15 mmol, 3 equiv) was added dropwise while maintaining the temperature of the mixture below 10 °C. Next, the sulfone (5 mmol, 1 equiv) was added in one portion. The resulting mixture was stirred for the given time (Table 1) at 75 °C. The mixture was cooled to room temperature, and the precipitate filtered off, washed with H2O, dried in air, and crystallized from 2-PrOH. See Supplementary data for the characterization of the bromination products obtained
References:
Borys, Krzysztof M.;Korzynski, MacIej D.;Ochal, Zbigniew [Tetrahedron Letters,2012,vol. 53,# 48,p. 6606 - 6610,5]
![Benzene,[(dibromomethyl)sulfonyl]-](/CAS/20180601/GIF/16003-66-0.gif)
16003-66-0
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17025-47-7
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35008-50-5
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17025-47-7
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5000-44-2
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17025-47-7
211 suppliers
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