N-Fmoc-N-Methyl-O-tert-butyl-L-threonine synthesis

1synthesis methods

Product Name:N-Fmoc-N-Methyl-O-tert-butyl-L-threonine
CAS Number:117106-20-4
Molecular formula:C24H29NO5
Molecular Weight:411.49

N-Fmoc-N-Methyl-O-tert-butyl-L-threonine, a threonine derivative, has been used to prepare the antifungal cyclic dipeptide petiline. It can be synthesized by acylation of O-tert-butyl-L-threonine in dioxane and fluorene methoxycarbonyl azide.

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N-Fmoc-N-Methyl-O-tert-butyl-L-threonine

117106-20-4
131 suppliers
$25.00/100mg

Yield:117106-20-4 45%

Reaction Conditions:

with sodium carbonate in 1,4-dioxane at 0; for 1.16667 h;

References:

Galpin;Mohammed;Patel [Tetrahedron,1988,vol. 44,# 6,p. 1773 - 1782]

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N-Fmoc-N-Methyl-O-tert-butyl-L-threonine Related Search:

tert-Butyl methyl ether Fmoc-Phe-OH Fmoc-Lys(Boc)-OH 2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-hydroxy-butanoic acid N-(9-Fluorenylmethoxycarbonyloxy)succinimide Fmoc-Asp(OtBu)-OH L-Threonine Nalpha-Fmoc-Ndelta-trityl-L-glutamine tert-Butanol tert-Butyldimethylsilyl chloride

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N-Fmoc-N-Methyl-O-tert-butyl-L-threonine synthesis

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