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ChemicalBook CAS DataBase List IMD-0354
978-62-1

IMD-0354 synthesis

4synthesis methods
-

Yield: 85.5%

Steps:

51 Example 51
Example 51 N-[3,5-Bis(trifluoromethyl)phenyl]-5-chloro-2-hydroxybenzamide (Comopund No. 50). Using 5-chlorosalicylic acid and 3,5-bis(trifluoromethyl)aniline as the raw materials, the same operation as the example 16 gave the title compound. Yield: 85.5%. 1H-NMR(DMSO-d6): δ 7.05(1H, d, J=8.7Hz), 7.49(1H, dd, J=8.7, 2.7Hz), 7.85(1H, s), 7.87(1H, d, J=2.7Hz), 8.45(2H, s), 10.85(1H, s), 11.39(1H, s).

References:

Institute of Medicinal Molecular Design, Inc. EP1352650, 2003, A1

IMD-0354 Related Search: