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ChemicalBook CAS DataBase List Docetaxel Impurity 15
146924-91-6

Docetaxel Impurity 15 synthesis

5synthesis methods
2,3-Azetidinedione, 1-(4-methoxyphenyl)-4-phenyl-, (4R)-

205518-66-7
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Docetaxel Impurity 15

146924-91-6
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Yield:146924-91-6 90%

Reaction Conditions:

with sodium tetrahydroborate in methanol at 0;stereoselective reaction;

References:

Chincholkar, Pinak M.;Kale, Ajaykumar S.;Gumaste, Vikas K.;Deshmukh, Abdul Rakeeb A.S. [Tetrahedron,2009,vol. 65,# 12,p. 2605 - 2609] Location in patent:experimental part

186613-02-5 Synthesis
3-(4-METHOXYPHENYL)-2-OXO-4-PHENYLCYCLOBUTYL ACETATE

186613-02-5
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Docetaxel Impurity 15

146924-91-6
13 suppliers
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Paclitaxel Impurity 9

146924-90-5
4 suppliers
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