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ChemicalBook CAS DataBase List DIISOPENTYL SULFIDE
544-02-5

DIISOPENTYL SULFIDE synthesis

10synthesis methods
-

Yield:544-02-5 88%

Reaction Conditions:

with tetrachloromethane;water;triethylamine in glycerol at 50; for 12 h;

Steps:


General procedure: A mixture of an alkyl halide (2 mmol), thiourea (2.5 mmol),Et3N (3.5 mmol) and CCl4 (2 mmol) in wet glycerol (2 mLglycerol + 0.1 mL H2O) was stirred magnetically at 50 °Cfor 12-24 h. Then H2O (1 mL) was added to the reactionmixture and the reaction was extracted with EtOAc(3 × 2 mL). The organic layers were decanted, combined,dried over Na2SO4, and concentrated to yield the crudedisulfide, which was further purified by silica gel chromatographyusing low-boiling petroleum ether as eluent toprovide the desired disulfides in good to excellent yields

References:

Abbasi, Mohammad;Khalili, Dariush [Journal of the Iranian Chemical Society,2015,vol. 12,# 8,art. no. 610,p. 1425 - 1430]

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