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ChemicalBook CAS DataBase List DI-TERT-BUTYLPHENYLPHOSPHONIUM TETRAFLUOROBORATE
612088-55-8

DI-TERT-BUTYLPHENYLPHOSPHONIUM TETRAFLUOROBORATE synthesis

2synthesis methods
-

Yield:612088-55-8 95%

Reaction Conditions:

Stage #1: diisobutylaluminium hydride;Dichlorophenylphosphine in toluene at 20 - 40; for 6 h;Inert atmosphere;
Stage #2: tert-butyl alcoholwith boron trifluoride diethyl etherate in water at 20 - 40; for 12 h;Time;

Steps:

1; 2; 3; 4 Example 4: Synthesis of di-tert-butylphenylphosphonium tetrafluoroborate

Under argon protection, add 1 L of toluene to the dry reactor, then add phenylphosphine dichloride (178 g, 1 mol), and add 1.0 M of diisobutylaluminum hydride solution in 3 L at 0-10 °C. Then, the temperature is raised to 20-40 o C for 6 hours, and then the reaction is quenched by adding 2 L of 1 N sodium hydroxide solution, and then liquid separation, extraction, and the organic layer is dried over anhydrous magnesium sulfate, and the organic phase is transferred to another dry reaction. After the addition, tert-butanol (148 g, 2 mol) and 47% by mass of boron trifluoride diethyl ether solution (1.8 kg, 6 mol) were added in sequence, and reacted at 20-40 ° C for 12 hours, and then quenched by adding water. A precipitate formed and suction filtered, and the solid was dried in vacuo to give 294 g of di-tert-butylphenylphosphonium tetrafluoroborate in a yield of 95%

References:

CN109438511,2019,A Location in patent:Paragraph 0008; 0009; 0010; 0011

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