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ChemicalBook CAS DataBase List Benzyltriethylammonium bromide
5197-95-5

Benzyltriethylammonium bromide synthesis

4synthesis methods
-

Yield:5197-95-5 98%

Reaction Conditions:

in tetrahydrofuran;ethanol at 25; for 24 h;Inert atmosphere;

Steps:

General Procedure
General procedure: In analogy to literature4, to a solution of benzyl halide 9 (1 equiv.) in THF (50 ml/g benzyl halide) were added 1.5 equiv. of trimethylamine 10 (33 wt% in EtOH).The resulting solution was stirred at RT for 24 hours, during which the product precipitated asa white solid. The resulting suspension was cooled to 0 °C, filtrated, washed with ice-cold Et2O and dried in vacuo to yield benzyl ammonium salts 6 in the reported yields.

References:

Roiser, Lukas;Robiette, Rapha?l;Waser, Mario [Synlett,2016,vol. 27,# 13,art. no. ST-2016-B0225-L,p. 1963 - 1968] Location in patent:supporting information

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