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99109-07-6

(αS,βS)-β-[(2-AMinophenyl)thio]-α-hydroxy-4-Methoxybenzenepropanoic Acid Methyl Ester synthesis

4synthesis methods
-

Yield:-

Reaction Conditions:

in toluene;

Steps:

2 EXAMPLE 2

EXAMPLE 2 A mixture of 40 g of methyl (2R,3S)-2,3-epoxy-3-(4-methoxyphenyl)propionate, 26.5 g of 2-aminothiophenol and 300 ml of toluene is heated at 110° to 115° C. for 1 hour, whereby the reaction mixture containing methyl (2S,3S)-3-[(2-aminophenyl)thio]-2-hydroxy-3-(4-methoxylphenyl)propionate is obtained.

References:

US5294706,1994,A