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ChemicalBook CAS DataBase List 4-METHYL-2-PHENYL-1,3-THIAZOLE-5-CARBONYL CHLORIDE
54001-18-2

4-METHYL-2-PHENYL-1,3-THIAZOLE-5-CARBONYL CHLORIDE synthesis

3synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: 93 percent / NaOH / ethanol; H2O / 1.5 h / 85 °C
2: SOCl2 / 3 h / Heating

References:

Sierra, Michael L.;Beneton, Veronique;Boullay, Anne-Benedict;Boyer, Thierry;Brewster, Andrew G.;Donche, Frederic;Forest, Marie-Claire;Fouchet, Marie-Helene;Gellibert, Francoise J.;Grillot, Didier A.;Lambert, Millard H.;Laroze, Alain;Le Grumelec, Christelle;Linget, Jean Michel;Montana, Valerie G.;Nguyen, Van-Loc;Nicodeme, Edwige;Patel, Vipul;Penfornis, Annie;Pineau, Olivier;Pohin, Danig;Potvain, Florent;Poulain, Geraldine;Ruault, Cecile Bertho;Saunders, Michael;Toum, Jerome;Xu, H. Eric;Xu, Robert X.;Pianetti, Pascal M. [Journal of Medicinal Chemistry,2007,vol. 50,# 4,p. 685 - 695]

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