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ChemicalBook CAS DataBase List 4-Amino-2,3-dichlorobenzonitrile
193090-61-8

4-Amino-2,3-dichlorobenzonitrile synthesis

3synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 4 steps
1: AcOH; NaOH
2: Br2
3: Pd(dba)2 / dimethylformamide
4: aq. HCl / ethanol

References:

Hamann, Lawrence G.;Manfredi, Mark C.;Sun, Chongqing;Krystek Jr., Stanley R.;Huang, Yanting;Bi, Yingzhi;Augeri, David J.;Wang, Tammy;Zou, Yan;Betebenner, David. A.;Fura, Aberra;Seethala, Ramakrishna;Golla, Rajasree;Kuhns, Joyce E.;Lupisella, John A.;Darienzo, Celia J.;Custer, Laura L.;Price, Jennifer L.;Johnson, James M.;Biller, Scott A.;Zahler, Robert;Ostrowski, Jacek [Bioorganic and Medicinal Chemistry Letters,2007,vol. 17,# 7,p. 1860 - 1864]

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