4-(1H-indol-3-yl)butanamide synthesis
- Product Name:4-(1H-indol-3-yl)butanamide
- CAS Number:6245-91-6
- Molecular formula:C12H14N2O
- Molecular Weight:202.25
133-32-4
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Yield:6245-91-6 96%
Reaction Conditions:
Stage #1: 4-indol-3-yl-butyric acidwith 1,1'-carbonyldiimidazole in tetrahydrofuran at 20; for 1.5 h;
Stage #2: with ammonia in tetrahydrofuran at 20; for 2.5 h;
References:
Mewshaw, Richard E.;Zhou, Dahui;Zhou, Ping;Shi, Xiaojie;Hornby, Geoffrey;Spangler, Taylor;Scerni, Rosemary;Smith, Deborah;Schechter, Lee E.;Andree, Terrance H. [Journal of Medicinal Chemistry,2004,vol. 47,# 15,p. 3823 - 3842]
15591-70-5
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105-60-2
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$5.00/25g
6245-91-6
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