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ChemicalBook CAS DataBase List 3-METHYL-2-PHENYLVALERIC ACID
7782-37-8

3-METHYL-2-PHENYLVALERIC ACID synthesis

2synthesis methods
-

Yield:7782-37-8 96%

Reaction Conditions:

Stage #1: phenylacetic acidwith n-butyllithium in tetrahydrofuran at 0; for 1.5 h;Inert atmosphere;
Stage #2: 2-butyl iodide in tetrahydrofuran; for 0.25 h;Inert atmosphere;

References:

Staudaher, Nicholas D.;Lovelace, Joseph;Johnson, Michael P.;Louie, Janis [Organic Syntheses,2017,vol. 94,p. 1 - 15]

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