3-Chloropropyne synthesis
- Product Name:3-Chloropropyne
- CAS Number:624-65-7
- Molecular formula:C3H3Cl
- Molecular Weight:74.51
2978-58-7
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$12.00/1g
624-65-7
371 suppliers
$25.00/5mL
Yield:624-65-7 97.98%
Reaction Conditions:
with 3,5-dichlorobenzoyl chloride;potassium carbonate in N,N-dimethyl-formamide at 20; for 5 h;Time;Reagent/catalyst;
Steps:
1-3 Example 1
Put 209.50 g of 3,5-dichlorobenzoyl chloride, 83.16 g of 3-amino-3-methyl-1-butyne, and 419.5 g of DMF (N,N-dimethylformamide) into the reactor, and start stirring , The temperature was raised to 20°C, 21.1g of potassium carbonate, 1.57g of cyclodextrin, and 4.72g of octyldodecanol xyloside were added to the reaction kettle and reacted for 5 hours. After the reaction was completed, 82.17g of water was added to the reaction solution, and two Chloroethane 246.52g, stand for stratification, add the stratified organic phase to a sulfuric acid solution with a concentration of 2.0mol/L3.0mol/L, adjust the pH to 67, cool to -5 and stir for 2 hours. Centrifugal filtration to obtain 250.96g of propargyl chloride product,The yield is 97.98%, and the purity is 99.15%
References:
CN112661660,2021,A Location in patent:Paragraph 0020-0021; 0022-0023; 0024-0025; 0026-0031
107-19-7
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$12.00/25g
624-65-7
371 suppliers
$25.00/5mL
106-96-7
338 suppliers
$31.00/25g
624-65-7
371 suppliers
$25.00/5mL
