3-BENZYLOXYBROMOBENZENE synthesis
- Product Name:3-BENZYLOXYBROMOBENZENE
- CAS Number:53087-13-1
- Molecular formula:C13H11BrO
- Molecular Weight:263.13
591-20-8
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100-39-0
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53087-13-1
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Yield:53087-13-1 100%
Reaction Conditions:
with potassium carbonate in acetone; for 15 h;Reflux;
Steps:
79.79-1 Preparation of 1-(benzyloxy)-3-bromobenzene
A solution of 3-bromophenol (3 g, 17.34 mmol) in acetone (100 mL) was added with benzyl bromide (2.2 mL, 19.07 mmol) and K2CO3 (7.0 g, 52.02 mmol), and the resulting mixture was refluxed for 15 hours. The reaction mixture was cooled to room temperature, filtered, and washed with acetone. The filtrate was concentrated and purified by silica gel chromatography to obtain the title compound (white solid, 5.1 g, 100% yield). 1H NMR (300 MHz, CDCl3) δ 7.50 - 7.30 (m, 5H), 7.20 - 7.01 (m, 3H), 6.98 - 6.80 (m, 1H), 5.05 (s, 2H).
References:
EP2963027,2016,A1 Location in patent:Paragraph 1227; 1228; 1229
591-20-8
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100-44-7
639 suppliers
$13.50/250G
53087-13-1
210 suppliers
$11.00/5g
89598-96-9
346 suppliers
$9.00/1g
100-39-0
431 suppliers
$10.00/10g
53087-13-1
210 suppliers
$11.00/5g
585-79-5
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100-51-6
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53087-13-1
210 suppliers
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591-20-8
346 suppliers
$10.00/1g
584-08-7
1192 suppliers
$5.00/100g
100-44-7
639 suppliers
$13.50/250G
53087-13-1
210 suppliers
$11.00/5g