ChemicalBook CAS DataBase List 3,5-Dibromobenzyl bromide

3,5-Dibromobenzyl bromide synthesis

4synthesis methods

Product Name:3,5-Dibromobenzyl bromide
CAS Number:56908-88-4
Molecular formula:C7H5Br3
Molecular Weight:328.83

1611-92-3 Synthesis

1611-92-3
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$6.00/5g

56908-88-4
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$6.00/1g

Yield:56908-88-4 74%

Reaction Conditions:

with NBS;dibenzoyl peroxide in Carbon tetrachloride; for 24 h;Reflux;

Steps:

1.c synthesis of Intermediate C

1,3-dibromo-5-toluene (4.96 g, 20 mmol) was dissolved in 150 ml of tetrachloromethane and then benzoyl peroxide (0.36 g, 1.5 mmol) and N-bromosuccinimide (3.74 g, 21 mmol) was added thereto, and the reaction mixture was heated under reflux for 24 hours. The reaction solution was then poured into water and extracted with methylene chloride. The organic compound was dried over magnesium sulfate and treated with dichloromethane / petroleum ether (v / v = 2: 3) was chromatographed on silica gel as a eluent, dried and steamed to give intermediate C (4.87 g, 74% yield) as a white solid.

References:

CN106946777,2017,A Location in patent:Paragraph 0060-0062

145691-59-4 Synthesis