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ChemicalBook CAS DataBase List 2-ISOPROPOXYETHANOL
109-59-1

2-ISOPROPOXYETHANOL synthesis

4synthesis methods
-

Yield:-

Reaction Conditions:

Trimethyl borate;hydrogen fluoride in water at 30; for 0.166667 h;

Steps:

8-10
Propylene oxide (4g) was added to an equimolar mixture of tert-butanol (0.2 mol, 14.8g), iso-propanol(12.0 g, 0.2 mol) and ethanol (0.2 mol, 9.2 g) . Then 0.1 ml of trimethyl borate was added and 0.3 ml of 48% aqueous HF. The reaction started immediately. After the consumption of the propylene oxide (30 min) the mixture was analyzed with GLC to show a mixture comprising mono- propoxylated derivatives of tert butanol, isopropanol and ethanol.

References:

SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. WO2006/34997, 2006, A1 Location in patent:Page/Page column 19-20

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