2-Butyl-4-chloro-5-formylimidazole synthesis
- Product Name:2-Butyl-4-chloro-5-formylimidazole
- CAS Number:83857-96-9
- Molecular formula:C8H11ClN2O
- Molecular Weight:186.64
79047-41-9
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$16.96/1gm:
83857-96-9
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$8.00/10g
Yield:83857-96-9 12.81 g (86%)
Reaction Conditions:
with manganese dioxide in dichloromethane;
Steps:
1.v (v)
(v) 2-n-Butyl-4-chloro-5-imidazolecarboxaldehyde A stirred mixture of 2-n-butyl-4-chloro-5-hydroxymethylimidazole (15.00 g, 0.0795 mol) and activated manganese dioxide (40.00 g) in 600 ml of methylene chloride was refluxed for 24 h using a water separator. The mixture was filtered hot through a Celite pad. The Celite pad was washed several times with hot methylene chloride. The washings were combined with the filtrate and concentrated in vacuo to give 12.81 g (86%) of the aldehyde as a white solid; mp 97°-98° C.
References:
US5728842,1998,A
288-32-4
1008 suppliers
$5.00/25g
79047-41-9
121 suppliers
$16.96/1gm:
83857-96-9
508 suppliers
$8.00/10g