2-Amino-5-bromopyrimidine synthesis
- Product Name:2-Amino-5-bromopyrimidine
- CAS Number:7752-82-1
- Molecular formula:C4H4BrN3
- Molecular Weight:174
109-12-6
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$6.00/10g
7752-82-1
438 suppliers
$13.00/25g
Yield:7752-82-1 97%
Reaction Conditions:
with N-Bromosuccinimide in acetonitrile at 20;Cooling with ice;Darkness;
Steps:
7.2 Step 2. Synthesis of 5-bromo-2-aminopyrimidine (Intermediate 2-4)
The 2-aminopyrimidine (2.5g, 26.29mmol) was dissolved in acetonitrile (25mL) was added N- bromosuccinimide (4.6g, 27.9mmol) under ice-cooling, stirred in the dark overnight at room temperature. Recovery of the solvent under reduced pressure, washed with water (100 mL) was washed, filtered off with suction, and dried in vacuo to give a white solid. Yield: 97%
References:
CN106588884,2017,A Location in patent:Paragraph 0210; 0214; 0215; 0216
504-29-0
552 suppliers
$5.00/5G
7752-82-1
438 suppliers
$13.00/25g
