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ChemicalBook CAS DataBase List 2,6-Pyridinedicarboxaldehyde
5431-44-7

2,6-Pyridinedicarboxaldehyde synthesis

12synthesis methods
-

Yield:5431-44-7 99%

Reaction Conditions:

with selenium(IV) dioxide in 1,4-dioxane; for 2 h;Reflux;

Steps:

3.3 Step 2) Preparation of pyridine-2,6-dicarbaldehyde

300 mg (2.17 mmol) of the compound prepared in the above step 2) was dissolved in 50 ml of 1,4-dioxane, 2.6 g (23.8 mmol) of selenium dioxide was added, and the mixture was refluxed with stirring for 2 hours. After completion of the reaction, the reaction mixture was cooled to room temperature and filtered through a celite-filled filter to remove selenium dioxide. The obtained filtrate was distilled under reduced pressure and dried under reduced pressure to give the title compound (300 mg, 99%).

References:

KR2015/77974,2015,A Location in patent:Paragraph 0038-0039; 0083-0085

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