ChemicalBook CAS DataBase List 2,5-PYRIDINEDICARBOXYLIC ACID

2,5-PYRIDINEDICARBOXYLIC ACID synthesis

10synthesis methods

Product Name:2,5-PYRIDINEDICARBOXYLIC ACID
CAS Number:100-26-5
Molecular formula:C7H5NO4
Molecular Weight:167.12

121-34-6
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100-26-5
361 suppliers
$8.00/5g

Yield:-

Reaction Conditions:

with disodium hydrogenphosphate;potassium dihydrogenphosphate;chloramphenicol;magnesium sulfate;ammonium chloride;thiostrepton A;sodium chloride;calcium chloride in water at 30; for 120 h;Enzymatic reaction;

Steps:

1 Production of 2,5-PDCA Using Vanillic Acid
(0187) Extracts from R. jostii (praA) containing recombinant praA gene grown for 5 days on M9 media containing 0.1% vanillic acid also generated a new metabolite at retention time 10.0 min with m/z 167.7 (MH⁺) and 189.7 (MNa⁺) matching the retention time and mass spectrum of authentic 2,5-PDCA. Peak 2,5-PDCA production was observed after 5 days. The yield was determined to be 80 mg 2,5-PDCA per litre culture from LC-MS analysis.

References:

Biome Bioplastics Limited;Law, Paul;Mines, Paul;Bugg, Timothy US2018/148752, 2018, A1 Location in patent:Paragraph 0182-0183; 0186-0187; 0197

FullText

104-90-5 Synthesis