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ChemicalBook CAS DataBase List 1-(4-Methylphenyl)ethanol
536-50-5

1-(4-Methylphenyl)ethanol synthesis

11synthesis methods
From p-tolymagnesium bromide and acetaldehyde in ether; from 4-methylaceto-phenone with sodium metal in ethanol
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Yield:536-50-5 93%

Reaction Conditions:

with C22H30B10Cl2FeN6O2;dihydrogen peroxide in methanol at 20; for 7 h;

Steps:

10

4-methylethylbenzene (1.0 mmol), iron complex 2 (0.05 mmol) and H2O2 (1.3 mmol) were dissolved in 2 mL of methanol and reacted at room temperature for 7 hours. After the reaction was completed, the reaction solution was concentrated and separated directly by silica gel column chromatography. Drying to the same mass yields the corresponding product C9H12O (93% yield).

References:

CN110627841,2019,A Location in patent:Paragraph 0069-0072

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