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ChemicalBook CAS DataBase List 1,4-Benzenedimethanol
589-29-7

1,4-Benzenedimethanol synthesis

12synthesis methods
-

Yield:589-29-7 80%

Reaction Conditions:

with water;sodium carbonate in 1,4-dioxane at 80; for 3 h;Solvent;Reagent/catalyst;Temperature;

Steps:

3 synthesis of 1,4-benzenedimethanol
100 g (0.38 mol) of 1,4-bis (bromomethyl) benzene,30g sodium carbonate,1000 g of soft water is mixed with 300 g of 1,4-dioxane,Heated to 80 for about 3 hours,Adding sodium carbonate aqueous solution and weakly alkaline,Most of the solvent of the organic layer was removed via the gyrotron concentrator.The crude product was extracted with ethyl acetate (400 g x 2 times)The organic layer was removed via a gyrotron concentrator to give 47 g of crude terephthalate.Para-xylylene crude product was recrystallized from ethyl acetate and cyclohexane to obtain 42g of high purity terephthalic acid product (yield 80.0%, purity 99.3%).

References:

Changxing Chemical Industry (China) Co., Ltd.;Chen Zhian;Li Junqin CN107324971, 2017, A Location in patent:Paragraph 0139-0174

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