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ChemicalBook CAS DataBase List 1,1'-Carbonyldiimidazole
530-62-1

1,1'-Carbonyldiimidazole synthesis

11synthesis methods
1,1'-Carbonyldiimidazole has been prepared by the reaction of imidazole and phosgene in anhydrous benzene and anhydrous tetrahydrofuran. It has also been obtained by the reaction of 1-(trimethylsilyl)imidazole and phosgene in anhydrous benzene, but that method offers no advantages that justify the more extensive preparative effort required.
DOI: 10.15227/orgsyn.048.0044
-

Yield:530-62-1 90.5%

Reaction Conditions:

in dichloromethane at 26; for 0.5 h;Inert atmosphere;Temperature;

Steps:

1.2; 1.3; 2.2; 2.3; 3.2; 3.3; 4.2; 4.3

Add 0.04 mol of triphosgene and 200 ml of dichloromethane to a three-necked flask.Stir until the phosgene dissolves,Cool the mixture to 26 ° C,Under nitrogen protection conditions,To the mixture, N-trimethylsilazole 0.28 mol was added dropwise.The dropping time is 30 min, that is, the product carbonyl diimidazole reaction liquid is obtained;(3) The carbonyl diimidazole reaction liquid prepared in the step (2) is filtered, and the filtered product is subjected to vacuum drying at a temperature of 72 ° C to obtain a powdery carbonyl diimidazole.

References:

CN109232430,2019,A Location in patent:Paragraph 0015; 0017; 0019; 0021; 0023; 0025; 0027-0032

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