α-Naphthoflavone
- $18 - $975
- Product name: α-Naphthoflavone
- CAS: 604-59-1
- MF: C19H12O2
- MW: 272.3
- EINECS:210-071-1
- MDL Number:MFCD00004985
- Synonyms:7,8-BENZOFLAVONE;ALPHA-NAPHTHOFLAVONE;A-NAPHTHOFLAVANONE;A-NAPHTHOFLAVONE;BENZOFLAVONE;NAPHTHOFLAVANONE, A-;NAPHTHOFLAVONE, A-;2-b)pyran-4-one,2-phenyl-4h-naphtho(
37 prices
Selected condition:
Brand
- AK Scientific
- Alfa Aesar
- American Custom Chemicals Corporation
- ApexBio Technology
- Apolloscientific
- Arctom
- AvaChem
- Biosynth Carbosynth
- Cayman Chemical
- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
- SynQuest Laboratories
- TCI Chemical
- TRC
Package
- 10mg
- 20mg
- 100mg
- 1G
- 5g
- 10g
- 25g
- 50g
- 100g
- 250g
- ManufacturerAK Scientific
- Product numberJ54118
- Product description2-Phenyl-4H-benzo[h]chromen-4-one
- Packaging5g
- Price$20
- Updated2021-12-16
- Buy
- ManufacturerAlfa Aesar
- Product numberA18542
- Product descriptionalpha-Naphthoflavone, 97%
- Packaging5g
- Price$51.65
- Updated2024-03-01
- Buy
- ManufacturerAlfa Aesar
- Product numberA18542
- Product descriptionalpha-Naphthoflavone, 97%
- Packaging25g
- Price$215.65
- Updated2024-03-01
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberPXT0004616
- Product descriptionALPHA-NAPHTHOFLAVONE 95.00%
- Packaging1G
- Price$430.2
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberPXT0004616
- Product descriptionALPHA-NAPHTHOFLAVONE 95.00%
- Packaging5G
- Price$469.3
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberPXT0004616
- Product descriptionALPHA-NAPHTHOFLAVONE 95.00%
- Packaging25G
- Price$746.5
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC3353
- Product descriptionα-Naphthoflavone
- Packaging10g
- Price$135
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberOR1158
- Product descriptionalpha-Naphthoflavone
- Packaging5g
- Price$111
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberOR1158
- Product descriptionalpha-Naphthoflavone
- Packaging25g
- Price$279
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberOR1158
- Product descriptionalpha-Naphthoflavone
- Packaging100g
- Price$595
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN94465
- Product description7,8-Benzoflavone
- Packaging20mg
- Price$40
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number4501
- Product descriptionalpha-Naphthylflavone
- Packaging10mg
- Price$29
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number4501
- Product descriptionalpha-Naphthylflavone
- Packaging20mg
- Price$39
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number4501
- Product descriptionalpha-Naphthylflavone
- Packaging100mg
- Price$49
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFB09432
- Product description7,8-Benzoflavone
- Packaging10g
- Price$40
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFB09432
- Product description7,8-Benzoflavone
- Packaging25g
- Price$70
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | J54118 | 2-Phenyl-4H-benzo[h]chromen-4-one | 5g | $20 | 2021-12-16 | Buy |
Alfa Aesar | A18542 | alpha-Naphthoflavone, 97% | 5g | $51.65 | 2024-03-01 | Buy |
Alfa Aesar | A18542 | alpha-Naphthoflavone, 97% | 25g | $215.65 | 2024-03-01 | Buy |
American Custom Chemicals Corporation | PXT0004616 | ALPHA-NAPHTHOFLAVONE 95.00% | 1G | $430.2 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | PXT0004616 | ALPHA-NAPHTHOFLAVONE 95.00% | 5G | $469.3 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | PXT0004616 | ALPHA-NAPHTHOFLAVONE 95.00% | 25G | $746.5 | 2021-12-16 | Buy |
ApexBio Technology | C3353 | α-Naphthoflavone | 10g | $135 | 2021-12-16 | Buy |
Apolloscientific | OR1158 | alpha-Naphthoflavone | 5g | $111 | 2021-12-16 | Buy |
Apolloscientific | OR1158 | alpha-Naphthoflavone | 25g | $279 | 2021-12-16 | Buy |
Apolloscientific | OR1158 | alpha-Naphthoflavone | 100g | $595 | 2021-12-16 | Buy |
Arctom | CFN94465 | 7,8-Benzoflavone | 20mg | $40 | 2021-12-16 | Buy |
AvaChem | 4501 | alpha-Naphthylflavone | 10mg | $29 | 2021-12-16 | Buy |
AvaChem | 4501 | alpha-Naphthylflavone | 20mg | $39 | 2021-12-16 | Buy |
AvaChem | 4501 | alpha-Naphthylflavone | 100mg | $49 | 2021-12-16 | Buy |
Biosynth Carbosynth | FB09432 | 7,8-Benzoflavone | 10g | $40 | 2021-12-16 | Buy |
Biosynth Carbosynth | FB09432 | 7,8-Benzoflavone | 25g | $70 | 2021-12-16 | Buy |
Properties
Melting point :153-157 °C (lit.)
Boiling point :375.35°C (rough estimate)
Density :1.1382 (rough estimate)
refractive index :1.5510 (estimate)
storage temp. :2-8°C
solubility :Chloroform (Slightly), Ethyl Acetate (Slightly)
form :Crystalline Powder or Crystals
color :yellow
BRN :210862
Stability :Stable. Incompatible with strong oxidizing agents.
LogP :5.003 (est)
CAS DataBase Reference :604-59-1(CAS DataBase Reference)
EPA Substance Registry System :4H-Naphtho[1,2-b]pyran-4-one, 2-phenyl- (604-59-1)
Boiling point :375.35°C (rough estimate)
Density :1.1382 (rough estimate)
refractive index :1.5510 (estimate)
storage temp. :2-8°C
solubility :Chloroform (Slightly), Ethyl Acetate (Slightly)
form :Crystalline Powder or Crystals
color :yellow
BRN :210862
Stability :Stable. Incompatible with strong oxidizing agents.
LogP :5.003 (est)
CAS DataBase Reference :604-59-1(CAS DataBase Reference)
EPA Substance Registry System :4H-Naphtho[1,2-b]pyran-4-one, 2-phenyl- (604-59-1)
Safety Information
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Signal word: | Warning | |||||||||||||||||||||
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Description
The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that promotes the expression of phase I and II xenobiotic chemical metabolizing enzyme genes, including the cytochrome P450 (CYP) isoforms CYP1A1 and CYP1A2. α-Naphthoflavone is a flavone that modulates xenobiotic metabolism at several points. It antagonizes AhR, blocking the expression of phase I and II genes at nanomolar concentrations, although it can agonize AhR at higher concentrations (10 μM). α-Naphthoflavone inhibits CYP19 (aromatase), CYP1A1, CYP1A2, and CYP1B1 (IC50s = 500, 60, 6, and 5 nM, respectively), whereas it activates CYP3A4 (Kd = 7.4 μM). Dietary α-naphthoflavone can contribute to carcinogenesis in the presence of synthetic estrogens.More related product prices
DEXTROMETHORPHAN Fluconazole Naringenin C.I. 75710 RHAPONTIN PONCIRIN 3,5-DIHYDROXY-4'-METHOXYSTILBENE 3-O-BETA-D-GLUCOSIDE α-NaphthoflavoneRelated product price
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$21-1220 - Fluconazole
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$5-6000
Suppliers and manufacturers
Capot Chemical Co.,Ltd.
Shanghai Daken Advanced Materials Co.,Ltd
Shanghai Zheyan Biotech Co., Ltd.
Chengdu GLP biotechnology Co Ltd
Chengdu Biopurify Phytochemicals Ltd.
Hubei Jusheng Technology Co.,Ltd.