WWL229
- $44 - $1800
- Product name: WWL229
- CAS: 1338575-28-2
- MF: C16H22N2O5
- MW: 322.36
- EINECS:
- MDL Number:MFCD28160858
- Synonyms:WWL229;XVBRVSAGMWRVCK-UHFFFAOYSA-N;Reaxys ID: 25732135;1-Piperidinecarboxylic acid, 2-(3-methoxypropyl)-, 4-nitrophenyl ester;WWL229 4-Nitrophenyl 2-(3-methoxypropyl) piperidine-1-carboxylate;WWL 229,WWL-229,Inhibitor,inhibit,WWL229
12 prices
Selected condition:
Brand
- AK Scientific
- Cayman Chemical
- DC Chemicals
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TRC
Package
- 1mg
- 2.5mg
- 5mg
- 10mg
- 25mg
- 100mg
- 1g
- ManufacturerAK Scientific
- Product numberSYN5249
- Product descriptionWWL229
- Packaging100mg
- Price$860
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number16182
- Product descriptionWWL229 ≥98%
- Packaging1mg
- Price$44
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16182
- Product descriptionWWL229 ≥98%
- Packaging5mg
- Price$109
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16182
- Product descriptionWWL229 ≥98%
- Packaging10mg
- Price$193
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16182
- Product descriptionWWL229
- Packaging25mg
- Price$426
- Updated2024-03-01
- Buy
- ManufacturerDC Chemicals
- Product numberDC21823
- Product descriptionWWL229 >98%
- Packaging1g
- Price$1800
- Updated2021-12-16
- Buy
- ManufacturerMedical Isotopes, Inc.
- Product number62618
- Product descriptionWWL229
- Packaging10mg
- Price$750
- Updated2021-12-16
- Buy
- ManufacturerSigma-Aldrich
- Product numberSML1180
- Product descriptionWWL229 ≥98% (HPLC)
- Packaging5mg
- Price$47.2
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberSML1180
- Product descriptionWWL229 ≥98% (HPLC)
- Packaging25mg
- Price$462
- Updated2024-03-01
- Buy
- ManufacturerTRC
- Product numberW700500
- Product descriptionWWL229
- Packaging2.5mg
- Price$90
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberW700500
- Product descriptionWWL229
- Packaging5mg
- Price$125
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberW700500
- Product descriptionWWL229
- Packaging25mg
- Price$310
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | SYN5249 | WWL229 | 100mg | $860 | 2021-12-16 | Buy |
Cayman Chemical | 16182 | WWL229 ≥98% | 1mg | $44 | 2024-03-01 | Buy |
Cayman Chemical | 16182 | WWL229 ≥98% | 5mg | $109 | 2024-03-01 | Buy |
Cayman Chemical | 16182 | WWL229 ≥98% | 10mg | $193 | 2024-03-01 | Buy |
Cayman Chemical | 16182 | WWL229 | 25mg | $426 | 2024-03-01 | Buy |
DC Chemicals | DC21823 | WWL229 >98% | 1g | $1800 | 2021-12-16 | Buy |
Medical Isotopes, Inc. | 62618 | WWL229 | 10mg | $750 | 2021-12-16 | Buy |
Sigma-Aldrich | SML1180 | WWL229 ≥98% (HPLC) | 5mg | $47.2 | 2024-03-01 | Buy |
Sigma-Aldrich | SML1180 | WWL229 ≥98% (HPLC) | 25mg | $462 | 2024-03-01 | Buy |
TRC | W700500 | WWL229 | 2.5mg | $90 | 2021-12-16 | Buy |
TRC | W700500 | WWL229 | 5mg | $125 | 2021-12-16 | Buy |
TRC | W700500 | WWL229 | 25mg | $310 | 2021-12-16 | Buy |
Properties
storage temp. :2-8°C
solubility :DMF: 30 mg/ml; DMSO: 25 mg/ml; Ethanol: 30 mg/ml; Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml
form :oil
color :colorless to light yellow
solubility :DMF: 30 mg/ml; DMSO: 25 mg/ml; Ethanol: 30 mg/ml; Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml
form :oil
color :colorless to light yellow
Safety Information
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Signal word: | Danger | ||||||||||||||||||||||||||||||
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Description
Mouse carboxylesterase 3 (Ces3, also named Ces1d) mediates triglyceride hydrolysis in white adipose tissue, liberating free fatty acids into circulation. Although important for basal lipolysis, Ces3 expression can be induced by xenobiotics. Ces3 activity is significantly elevated during adipocyte differentiation. WWL229 is a selective inhibitor of Ces3 (IC50 = 1.94 μM) that has no significant effect on other, related enzymes. By inhibiting the triglyceride hydrolase activity of Ces3, WWL229 promotes lipid storage in cultured adipocytes and prevents basal lipolysis.Suppliers and manufacturers
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