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ChemicalBook >> CAS DataBase List >> Vadadustat

Vadadustat

Vadadustat price.
  • $62 - $1900
  • Product name: Vadadustat
  • CAS: 1000025-07-9
  • MF: C14H11ClN2O4
  • MW: 306.7
  • EINECS:
  • MDL Number:MFCD30470233
  • Synonyms:Vadadustat;AKB-6548; AKB 6548; AKB6548; PG-1016548; PG 1016548; PG1016548; B-506; B506; VADADUSTAT;PG-1016548;AKB-6548;Vadadustat(AKB-6548/PG-1016548);Vadadustat (AKB-6548);AKB-6548;PG 1016548;PG1016548
23 prices
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  • Activate Scientific
  • AK Scientific
  • Axon Medchem
  • Biosynth Carbosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • TRC
Package
  • 2mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerActivate Scientific
  • Product numberAS117671
  • Product descriptionVadadustat 97+%
  • Packaging25mg
  • Price$534
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number8314BB
  • Product descriptionVadadustat
  • Packaging100mg
  • Price$590
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon3288
  • Product descriptionVadadustat-AKB6548|PG-1016548 99%
  • Packaging10mg
  • Price$88
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFV168206
  • Product descriptionVadadustat
  • Packaging100mg
  • Price$400
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFV168206
  • Product descriptionVadadustat
  • Packaging50mg
  • Price$250
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFV168206
  • Product descriptionVadadustat
  • Packaging25mg
  • Price$200
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFV168206
  • Product descriptionVadadustat
  • Packaging10mg
  • Price$120
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFV168206
  • Product descriptionVadadustat
  • Packaging5mg
  • Price$75
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number15295
  • Product descriptionVadadustat
  • Packaging50mg
  • Price$357
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number15295
  • Product descriptionVadadustat
  • Packaging25mg
  • Price$239
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number15295
  • Product descriptionVadadustat
  • Packaging10mg
  • Price$109
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number15295
  • Product descriptionVadadustat
  • Packaging5mg
  • Price$62
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6373
  • Product descriptionVadadustat 99.25%
  • Packaging2mg
  • Price$70
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6373
  • Product descriptionVadadustat 99.25%
  • Packaging5mg
  • Price$120
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6373
  • Product descriptionVadadustat 99.25%
  • Packaging10mg
  • Price$190
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6373
  • Product descriptionVadadustat 99.25%
  • Packaging50mg
  • Price$490
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Activate Scientific AS117671 Vadadustat 97+% 25mg $534 2021-12-16 Buy
AK Scientific 8314BB Vadadustat 100mg $590 2021-12-16 Buy
Axon Medchem Axon3288 Vadadustat-AKB6548|PG-1016548 99% 10mg $88 2021-12-16 Buy
Biosynth Carbosynth FV168206 Vadadustat 100mg $400 2021-12-16 Buy
Biosynth Carbosynth FV168206 Vadadustat 50mg $250 2021-12-16 Buy
Biosynth Carbosynth FV168206 Vadadustat 25mg $200 2021-12-16 Buy
Biosynth Carbosynth FV168206 Vadadustat 10mg $120 2021-12-16 Buy
Biosynth Carbosynth FV168206 Vadadustat 5mg $75 2021-12-16 Buy
Cayman Chemical 15295 Vadadustat 50mg $357 2024-03-01 Buy
Cayman Chemical 15295 Vadadustat 25mg $239 2024-03-01 Buy
Cayman Chemical 15295 Vadadustat 10mg $109 2024-03-01 Buy
Cayman Chemical 15295 Vadadustat 5mg $62 2024-03-01 Buy
ChemScene CS-6373 Vadadustat 99.25% 2mg $70 2021-12-16 Buy
ChemScene CS-6373 Vadadustat 99.25% 5mg $120 2021-12-16 Buy
ChemScene CS-6373 Vadadustat 99.25% 10mg $190 2021-12-16 Buy
ChemScene CS-6373 Vadadustat 99.25% 50mg $490 2021-12-16 Buy

Properties

Melting point :172-174°C
Boiling point :674.6±55.0 °C(Predicted)
Density :1.461±0.06 g/cm3(Predicted)
storage temp. :Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility :DMSO (Slightly), Methanol (Slightly)
form :Solid
pka :4.09±0.40(Predicted)
color :Pale Beige to Light Beige
Stability :Hygroscopic

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H373 May cause damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 2 Warning P260, P314, P501
Precautionary statements:
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P314 Get medical advice/attention if you feel unwell.
P330 Rinse mouth.
P501 Dispose of contents/container to..…

Description

Vadadustat is an inhibitor of hypoxia-inducible factor prolyl hydroxylase 2 (HIF-PH2) and HIF-PH3 (IC50s = 1.1 and 0.39 micromolar, respectively). It stabilizes HIF-1α in mouse hepatocyte nuclear extracts. Vadadustat (50 and 100 mg/kg) increases erythropoietin levels in mouse serum.