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ChemicalBook >> CAS DataBase List >> TOFOGLIFLOZIN

TOFOGLIFLOZIN

TOFOGLIFLOZIN price.
  • $32 - $4500
  • Product name: TOFOGLIFLOZIN
  • CAS: 1201913-82-7
  • MF: C22H26O6.H2O
  • MW: 404.46
  • EINECS:
  • MDL Number:MFCD28385880
  • Synonyms:Tofogliflozin (hydrate);(1S,3'R,4'S,5'S,6'R)-6-[(4-Ethylphenyl)methyl]-3',4',5',6'-tetrahydro-6'-(hydroxymethyl)spiro[isobenzofuran-1(3H),2'-[2H]pyran]-3',4',5'-triol hydrate (1:1);Tofogliflozin hydrate (1:1);Tofogliflozin hydrate (1:1)-API;Tofogliflozin anyhydrous;UNII-554245W62TTofogliflozin [INN];CSG 452(hydrate);(3S,3'R,4'S,5'S,6'R)-5-[(4-ethylphenyl)methyl]-6'-(hydroxymethyl)spiro[1H-2-benzofuran-3,2'-oxane]-3',4',5'-triol,hydrate
13 prices
Selected condition：
Brand
  • AK Scientific
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 250mg
  • ManufacturerAK Scientific
  • Product number8832DG
  • Product descriptionTofogliflozinhydrate
  • Packaging10mg
  • Price$353
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number23509
  • Product descriptionTofogliflozin (hydrate) ≥95%
  • Packaging1mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number23509
  • Product descriptionTofogliflozin (hydrate) ≥95%
  • Packaging5mg
  • Price$139
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number23509
  • Product descriptionTofogliflozin (hydrate) ≥95%
  • Packaging10mg
  • Price$230
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number23509
  • Product descriptionTofogliflozin (hydrate) ≥95%
  • Packaging25mg
  • Price$420
  • Updated2024-03-01
  • Buy
  • ManufacturerChemenu
  • Product numberCM139397
  • Product description(1S,3''R,4''S,5''S,6''R)-6-(4-ethylbenzyl)-6''-(hydroxymethyl)-3'',4'',5'',6''-tetrahydro-3H-spiro[isobenzofuran-1,2''-pyran]-3'',4'',5''-triolhydrate 98%
  • Packaging10mg
  • Price$524
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-3792
  • Product descriptionTofogliflozin(hydrate) 98.85%
  • Packaging5mg
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-3792
  • Product descriptionTofogliflozin(hydrate) 98.85%
  • Packaging10mg
  • Price$160
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-3792
  • Product descriptionTofogliflozin(hydrate) 98.85%
  • Packaging50mg
  • Price$540
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004313
  • Product descriptionTofogliflozinhydrate 98+%
  • Packaging5mg
  • Price$350
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004313
  • Product descriptionTofogliflozinhydrate 98+%
  • Packaging10mg
  • Price$560
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004313
  • Product descriptionTofogliflozinhydrate 98+%
  • Packaging50mg
  • Price$1820
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC7826
  • Product descriptionTofogliflozinhydrate >98%
  • Packaging250mg
  • Price$4500
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 8832DG Tofogliflozinhydrate 10mg $353 2021-12-16 Buy
Cayman Chemical 23509 Tofogliflozin (hydrate) ≥95% 1mg $32 2024-03-01 Buy
Cayman Chemical 23509 Tofogliflozin (hydrate) ≥95% 5mg $139 2024-03-01 Buy
Cayman Chemical 23509 Tofogliflozin (hydrate) ≥95% 10mg $230 2024-03-01 Buy
Cayman Chemical 23509 Tofogliflozin (hydrate) ≥95% 25mg $420 2024-03-01 Buy
Chemenu CM139397 (1S,3''R,4''S,5''S,6''R)-6-(4-ethylbenzyl)-6''-(hydroxymethyl)-3'',4'',5'',6''-tetrahydro-3H-spiro[isobenzofuran-1,2''-pyran]-3'',4'',5''-triolhydrate 98% 10mg $524 2021-12-16 Buy
ChemScene CS-3792 Tofogliflozin(hydrate) 98.85% 5mg $100 2021-12-16 Buy
ChemScene CS-3792 Tofogliflozin(hydrate) 98.85% 10mg $160 2021-12-16 Buy
ChemScene CS-3792 Tofogliflozin(hydrate) 98.85% 50mg $540 2021-12-16 Buy
Crysdot CD31004313 Tofogliflozinhydrate 98+% 5mg $350 2021-12-16 Buy
Crysdot CD31004313 Tofogliflozinhydrate 98+% 10mg $560 2021-12-16 Buy
Crysdot CD31004313 Tofogliflozinhydrate 98+% 50mg $1820 2021-12-16 Buy
DC Chemicals DC7826 Tofogliflozinhydrate >98% 250mg $4500 2021-12-16 Buy

Properties

storage temp. :Store at -20°C
solubility :DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml; Ethanol:PBS (pH7.2)(1:20): 0.05 mg/ml
form :A crystalline solid
color :White to off-white

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Tofogliflozin hydrate, which is a sodium-glucose co-transporter 2 inhibitor, was approved in Japan for the treatment of type 2 diabetes at the same time as luseogliflozin hydrate (XIX). The drug was discovered by Chugai Pharmaceutical and jointly developed with Sanofi-Aventis and Kowa. Tofogliflozin hydrate reduces glucose levels by inhibiting the reuptake of glucose by selectively inhibiting SGLT2, and plays a key role in the reuptake of glucose in the proximal tubule of the kidneys.

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