Synephrine hydrochloride
- $38 - $3234
- Product name: Synephrine hydrochloride
- CAS: 5985-28-4
- MF: C9H14ClNO2
- MW: 203.67
- EINECS:227-804-6
- MDL Number:MFCD00050566
- Synonyms:1-(4-Hydroxyphenyl)-2-(methylamino)-ethanol hydrochloride;4-hydroxy-alpha-((methylamino)methyl)-benzenemethanohydrochloride ;l-1-p-hydroxyphenyl-2-methylamino-1-ethanolhydrochloride ;p-hydroxy-alpha-((methylamino)methyl)-benzylalcohohydrochloride ;p-hydroxy-alpha-(methylaminomethyl)benzylalcoholhydrochloride ;p-methylaminoaethanolphenolhydrochlorid ;SYNEPHRINE HCL;SYNEPHRINE HYDROCHLORIDE
16 prices
Selected condition:
Brand
- AK Scientific
- American Custom Chemicals Corporation
- Biorbyt Ltd
- Cayman Chemical
- ChemScene
- Crysdot
- Matrix Scientific
- SynQuest Laboratories
- TRC
Package
- 20mg
- 25mg
- 100mg
- 500mg
- 5G
- 10g
- 25g
- 50G
- 100g
- ManufacturerAK Scientific
- Product numberJ10611
- Product descriptionSynephrinehydrochloride
- Packaging25mg
- Price$38
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberNUT0000118
- Product descriptionSYNEPHRINE HYDROCHLORIDE 95.00%
- Packaging5G
- Price$866.25
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberNUT0000118
- Product descriptionSYNEPHRINE HYDROCHLORIDE 95.00%
- Packaging50G
- Price$3234
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb594320
- Product descriptionSynephrine hydrochloride
- Packaging20mg
- Price$187
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb594320
- Product descriptionSynephrine hydrochloride
- Packaging100mg
- Price$241.4
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number28398
- Product description(±)-Synephrine (hydrochloride)
- Packaging5g
- Price$57
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number28398
- Product description(±)-Synephrine (hydrochloride)
- Packaging10g
- Price$95
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number28398
- Product description(±)-Synephrine (hydrochloride)
- Packaging25g
- Price$152
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number28398
- Product description(±)-Synephrine (hydrochloride)
- Packaging50g
- Price$220
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-3083
- Product descriptionSynephrine(hydrochloride) 99.57%
- Packaging100mg
- Price$60
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-3083
- Product descriptionSynephrine(hydrochloride) 99.57%
- Packaging500mg
- Price$120
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31001346
- Product descriptionSynephrinehydrochloride 95%
- Packaging100g
- Price$91
- Updated2021-12-16
- Buy
- ManufacturerMatrix Scientific
- Product number076117
- Product description4-(1-Hydroxy-2-(methylamino)-ethyl)phenol hydrochloride 95+%
- Packaging10g
- Price$70
- Updated2021-12-16
- Buy
- ManufacturerMatrix Scientific
- Product number076117
- Product description4-(1-Hydroxy-2-(methylamino)-ethyl)phenol hydrochloride 95+%
- Packaging100g
- Price$360
- Updated2021-12-16
- Buy
- ManufacturerSynQuest Laboratories
- Product number4656-5-90
- Product description4-[1-Hydroxy-2-(methylamino)ethyl]phenol hydrochloride
- Packaging25g
- Price$228
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberS920001
- Product descriptionrac-SynephrineHydrochloride
- Packaging100g
- Price$410
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | J10611 | Synephrinehydrochloride | 25mg | $38 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | NUT0000118 | SYNEPHRINE HYDROCHLORIDE 95.00% | 5G | $866.25 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | NUT0000118 | SYNEPHRINE HYDROCHLORIDE 95.00% | 50G | $3234 | 2021-12-16 | Buy |
Biorbyt Ltd | orb594320 | Synephrine hydrochloride | 20mg | $187 | 2021-12-16 | Buy |
Biorbyt Ltd | orb594320 | Synephrine hydrochloride | 100mg | $241.4 | 2021-12-16 | Buy |
Cayman Chemical | 28398 | (±)-Synephrine (hydrochloride) | 5g | $57 | 2024-03-01 | Buy |
Cayman Chemical | 28398 | (±)-Synephrine (hydrochloride) | 10g | $95 | 2024-03-01 | Buy |
Cayman Chemical | 28398 | (±)-Synephrine (hydrochloride) | 25g | $152 | 2024-03-01 | Buy |
Cayman Chemical | 28398 | (±)-Synephrine (hydrochloride) | 50g | $220 | 2024-03-01 | Buy |
ChemScene | CS-3083 | Synephrine(hydrochloride) 99.57% | 100mg | $60 | 2021-12-16 | Buy |
ChemScene | CS-3083 | Synephrine(hydrochloride) 99.57% | 500mg | $120 | 2021-12-16 | Buy |
Crysdot | CD31001346 | Synephrinehydrochloride 95% | 100g | $91 | 2021-12-16 | Buy |
Matrix Scientific | 076117 | 4-(1-Hydroxy-2-(methylamino)-ethyl)phenol hydrochloride 95+% | 10g | $70 | 2021-12-16 | Buy |
Matrix Scientific | 076117 | 4-(1-Hydroxy-2-(methylamino)-ethyl)phenol hydrochloride 95+% | 100g | $360 | 2021-12-16 | Buy |
SynQuest Laboratories | 4656-5-90 | 4-[1-Hydroxy-2-(methylamino)ethyl]phenol hydrochloride | 25g | $228 | 2021-12-16 | Buy |
TRC | S920001 | rac-SynephrineHydrochloride | 100g | $410 | 2021-12-16 | Buy |
Properties
Melting point :147-150°C
storage temp. :Refrigerator
solubility :Methanol (Slightly), Water (Slightly)
form :Solid
color :Off-White to Pale Beige
InChI :InChI=1S/C9H13NO2.ClH/c1-10-6-9(12)7-2-4-8(11)5-3-7;/h2-5,9-12H,6H2,1H3;1H
InChIKey :COTCEGYSNTWJQV-UHFFFAOYSA-N
SMILES :C1(=CC=C(O)C=C1)C(O)CNC.Cl
LogP :-0.030 (est)
CAS DataBase Reference :5985-28-4(CAS DataBase Reference)
storage temp. :Refrigerator
solubility :Methanol (Slightly), Water (Slightly)
form :Solid
color :Off-White to Pale Beige
InChI :InChI=1S/C9H13NO2.ClH/c1-10-6-9(12)7-2-4-8(11)5-3-7;/h2-5,9-12H,6H2,1H3;1H
InChIKey :COTCEGYSNTWJQV-UHFFFAOYSA-N
SMILES :C1(=CC=C(O)C=C1)C(O)CNC.Cl
LogP :-0.030 (est)
CAS DataBase Reference :5985-28-4(CAS DataBase Reference)
Safety Information
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Signal word: | Warning | ||||||||||||||||||||||||||||
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Description
(±)-Synephrine is an alkaloid with vasoconstrictor and metabolic activities. It binds to α1A-, α2A-, and α2C-adrenergic receptors (ARs; Kis = 78, 36.7, and 24.4 μM, respectively). (±)-Synephrine is an agonist of α1A-ARs in HEK293 cells (EC50 = 4 μM in a reporter assay) but not in CHO cells expressing α2A- or α2C-AR. It also acts as an antagonist of α1A-, α2A-, and α2C-ARs, inhibiting L-phenylephrine-induced activation of α1A-AR in HEK293 cells and activation of α2A- and α2C-ARs induced by the α2-AR agonist medetomidine in CHO cells (IC50s = 12.8, 26, and 27.3 μM, respectively, in reporter assays). (±)-Synephrine induces contractions in isolated rabbit aortic rings (EC50 = 6.2 μg/ml) and increases ligation-induced mean arterial pressure in rats when administered at a dose of 2 mg/kg per day. It induces lipolysis in isolated rat and human adipocytes when used at concentrations of 100 and 1,000 μg/ml. (±)-Synephrine (50 μM) increases phosphorylation of Akt and AMP-activated protein kinase (AMPK) and translocation of Glut4 to the plasma membrane, as well as increases insulin-induced glucose consumption in L6 muscle cells when used at concentrations ranging from 25 to 200 μM.More related product prices
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