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ChemicalBook >> CAS DataBase List >> SB 239063

SB 239063

SB 239063 price.
  • $37 - $2300
  • Product name: SB 239063
  • CAS: 193551-21-2
  • MF: C20H21FN4O2
  • MW: 368.4
  • EINECS:
  • MDL Number:MFCD03792786
  • Synonyms:SB 239063;TRANS-1-(4-HYDROXYCYCLOHEXYL)-4-(4-FLUOROPHENYL)-5-(2-METHOXYPYRIDIMIDIN-4-YL)IMIDAZOLE;TRANS-1-(4-HYDROXYCYCLOHEXYL)-4-(4-FLUOROPHENYL)-5-(2-METHOXYPYRIMIDIN-4-YL) IMIDAZOLE;TRANS-1-(4-HYDROXYCYCLOHEXYL)-4-(FLUOROPHENYL)-5-(2-METHOXYPYRIMIDIN-4-YL) IMIDAZOLE;TRANS-4-[4-(4-FLUOROPHENYL)-5-(2-METHOXY-4-PYRIMIDINYL)-1H-IMIDAZOL-1-YL]CYCLOHEXANOL;Cyclohexanol, 4-[4-(4-fluorophenyl)-5-(2-methoxy-4-pyrimidinyl)-1H-imidazol-1-yl]-, trans-;SB 239063 - CAS 798558-40-4 - Calbiochem;CS-402
29 prices
Selected condition：
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Biosynth Carbosynth
  • Cayman Chemical
  • ChemScene
  • CSNpharm
  • DC Chemicals
  • Sigma-Aldrich
  • TCI Chemical
  • Tocris
  • TRC
  • Usbiological
Package
  • 1mg
  • 10mg
  • 25mg
  • 500μg
  • 5MG
  • 10
  • 50mg
  • 100mg
  • 250MG
  • 1g
  • 10mM(in 1mL DMSO)
  • ManufacturerAK Scientific
  • Product number4026AH
  • Product descriptiontrans-1-(4-Hydroxycyclohexyl)-4-(4-fluorophenyl)-5-(2-methoxypyrimidin-4-yl)imidazole
  • Packaging25mg
  • Price$555
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0000227
  • Product descriptionSB 239063 95.00%
  • Packaging5MG
  • Price$392.7
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0000227
  • Product descriptionSB 239063 95.00%
  • Packaging25MG
  • Price$739.2
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0000227
  • Product descriptionSB 239063 95.00%
  • Packaging250MG
  • Price$1871.1
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3792
  • Product descriptionSB 239063
  • Packaging5mg
  • Price$99
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3792
  • Product descriptionSB 239063
  • Packaging10mM(in 1mL DMSO)
  • Price$121
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3792
  • Product descriptionSB 239063
  • Packaging25mg
  • Price$349
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFS102257
  • Product descriptionSB 239063
  • Packaging10mg
  • Price$185
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFS102257
  • Product descriptionSB 239063
  • Packaging50mg
  • Price$647.5
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number19142
  • Product descriptionSB 239063 ≥98%
  • Packaging500μg
  • Price$37
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19142
  • Product descriptionSB 239063 ≥98%
  • Packaging1mg
  • Price$68
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19142
  • Product descriptionSB 239063 ≥98%
  • Packaging5mg
  • Price$127
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0072
  • Product descriptionSB 239063 99.80%
  • Packaging1mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0072
  • Product descriptionSB 239063 99.80%
  • Packaging5mg
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0072
  • Product descriptionSB 239063 99.80%
  • Packaging10mg
  • Price$180
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0072
  • Product descriptionSB 239063 99.80%
  • Packaging25mg
  • Price$390
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 4026AH trans-1-(4-Hydroxycyclohexyl)-4-(4-fluorophenyl)-5-(2-methoxypyrimidin-4-yl)imidazole 25mg $555 2021-12-16 Buy
American Custom Chemicals Corporation KIN0000227 SB 239063 95.00% 5MG $392.7 2021-12-16 Buy
American Custom Chemicals Corporation KIN0000227 SB 239063 95.00% 25MG $739.2 2021-12-16 Buy
American Custom Chemicals Corporation KIN0000227 SB 239063 95.00% 250MG $1871.1 2021-12-16 Buy
ApexBio Technology A3792 SB 239063 5mg $99 2021-12-16 Buy
ApexBio Technology A3792 SB 239063 10mM(in 1mL DMSO) $121 2021-12-16 Buy
ApexBio Technology A3792 SB 239063 25mg $349 2021-12-16 Buy
Biosynth Carbosynth FS102257 SB 239063 10mg $185 2021-12-16 Buy
Biosynth Carbosynth FS102257 SB 239063 50mg $647.5 2021-12-16 Buy
Cayman Chemical 19142 SB 239063 ≥98% 500μg $37 2024-03-01 Buy
Cayman Chemical 19142 SB 239063 ≥98% 1mg $68 2024-03-01 Buy
Cayman Chemical 19142 SB 239063 ≥98% 5mg $127 2024-03-01 Buy
ChemScene CS-0072 SB 239063 99.80% 1mg $50 2021-12-16 Buy
ChemScene CS-0072 SB 239063 99.80% 5mg $100 2021-12-16 Buy
ChemScene CS-0072 SB 239063 99.80% 10mg $180 2021-12-16 Buy
ChemScene CS-0072 SB 239063 99.80% 25mg $390 2021-12-16 Buy

Properties

Melting point :206-207.2 °C
storage temp. :2-8°C
solubility :DMSO: 11 mg/mL
form :White solid
color :white
InChIKey :ZQUSFAUAYSEREK-WKILWMFISA-N

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P330 Rinse mouth.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

SB 239063 is a selective p38 MAPK inhibitor (IC50 = 44 nM for recombinant purified p38α). It displays greater than 220-fold selectivity for p38 MAPK over ERK, JNK1, and other kinases. SB 239063 has been shown to reduce inflammatory cytokine production in lipopolysaccharide-stimulated human peripheral blood monocytes (IC50s = 0.12 and 0.35 μM, respectively for IL-1 and TNF-α) and is neuroprotective following oral administration in a rat model of cerebral focal ischemia.

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