PRIMA-1
- $19 - $2325
- Product name: PRIMA-1
- CAS: 5608-24-2
- MF: C9H15NO3
- MW: 185.22
- EINECS:
- MDL Number:MFCD19199989
- Synonyms:PRIMA-1;P53 REACTIVATION AND INDUCTION OF MASSIVE APOPTOSIS;2,2-BIS(HYDROXYMETHYL)-1-AZABICYCLO[2,2,2]OCTAN-3-ONE;2,2-BIS(HYDROXYMETHYL)-3-QUINUCLIDINONE;2,2-dimethylolquinuclidin-3-one;7,7-bis(hydroxymethyl)-1-azabicyclo[2.2.2]octan-8-one;PRIMA-1 - CAS 5608-24-2 - Calbiochem;2-Bis(hydroxymethyl)-3-quinuclidinone
34 prices
Selected condition:
Brand
- AHH
- AK Scientific
- Alfa Aesar
- Ambeed
- ApexBio Technology
- Arctom
- Cayman Chemical
- Crysdot
- CSNpharm
- DC Chemicals
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 1mg
- 10
- 1unit
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 50
- 1g
- 10mM(in 1mL DMSO)
- ManufacturerAHH
- Product numberAPI-1964
- Product descriptionPRIMA-1 Prima-1
- Packaging1g
- Price$1200
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number1997AH
- Product description2,2-Bis(hydroxymethyl)-3-quinuclidinone
- Packaging5mg
- Price$124
- Updated2021-12-16
- Buy
- ManufacturerAlfa Aesar
- Product numberJ64071
- Product descriptionPRIMA-1
- Packaging10mg
- Price$219.65
- Updated2024-03-01
- Buy
- ManufacturerAmbeed
- Product numberA755385
- Product descriptionPRIMA-1 98%
- Packaging5mg
- Price$51
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA755385
- Product descriptionPRIMA-1 98%
- Packaging10mg
- Price$77
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA755385
- Product descriptionPRIMA-1 98%
- Packaging25mg
- Price$134
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA755385
- Product descriptionPRIMA-1 98%
- Packaging50mg
- Price$173
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA755385
- Product descriptionPRIMA-1 98%
- Packaging100mg
- Price$224
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA755385
- Product descriptionPRIMA-1 98%
- Packaging1g
- Price$2325
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4483
- Product descriptionPRIMA-1
- Packaging1unit
- Price$28
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4483
- Product descriptionPRIMA-1
- Packaging10mM(in 1mL DMSO)
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4483
- Product descriptionPRIMA-1
- Packaging5mg
- Price$56
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4483
- Product descriptionPRIMA-1
- Packaging10mg
- Price$75
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4483
- Product descriptionPRIMA-1
- Packaging50mg
- Price$245
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS658179
- Product descriptionPRIMA-1 98%
- Packaging5mg
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number63520
- Product descriptionPRIMA-1 ≥95%
- Packaging1mg
- Price$19
- Updated2024-03-01
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AHH | API-1964 | PRIMA-1 Prima-1 | 1g | $1200 | 2021-12-16 | Buy |
AK Scientific | 1997AH | 2,2-Bis(hydroxymethyl)-3-quinuclidinone | 5mg | $124 | 2021-12-16 | Buy |
Alfa Aesar | J64071 | PRIMA-1 | 10mg | $219.65 | 2024-03-01 | Buy |
Ambeed | A755385 | PRIMA-1 98% | 5mg | $51 | 2021-12-16 | Buy |
Ambeed | A755385 | PRIMA-1 98% | 10mg | $77 | 2021-12-16 | Buy |
Ambeed | A755385 | PRIMA-1 98% | 25mg | $134 | 2021-12-16 | Buy |
Ambeed | A755385 | PRIMA-1 98% | 50mg | $173 | 2021-12-16 | Buy |
Ambeed | A755385 | PRIMA-1 98% | 100mg | $224 | 2021-12-16 | Buy |
Ambeed | A755385 | PRIMA-1 98% | 1g | $2325 | 2021-12-16 | Buy |
ApexBio Technology | A4483 | PRIMA-1 | 1unit | $28 | 2021-12-16 | Buy |
ApexBio Technology | A4483 | PRIMA-1 | 10mM(in 1mL DMSO) | $50 | 2021-12-16 | Buy |
ApexBio Technology | A4483 | PRIMA-1 | 5mg | $56 | 2021-12-16 | Buy |
ApexBio Technology | A4483 | PRIMA-1 | 10mg | $75 | 2021-12-16 | Buy |
ApexBio Technology | A4483 | PRIMA-1 | 50mg | $245 | 2021-12-16 | Buy |
Arctom | AS658179 | PRIMA-1 98% | 5mg | $50 | 2021-12-16 | Buy |
Cayman Chemical | 63520 | PRIMA-1 ≥95% | 1mg | $19 | 2024-03-01 | Buy |
Properties
Melting point :146-147 °C
Boiling point :353.7±17.0 °C(Predicted)
Density :1.32±0.1 g/cm3(Predicted)
storage temp. :Inert atmosphere,2-8°C
solubility :H2O: >10mg/mL
pka :13.68±0.10(Predicted)
form :solid
color :white to off-white
Water Solubility :Soluble in water at 10mg/ml
Sensitive :Light Sensitive
Boiling point :353.7±17.0 °C(Predicted)
Density :1.32±0.1 g/cm3(Predicted)
storage temp. :Inert atmosphere,2-8°C
solubility :H2O: >10mg/mL
pka :13.68±0.10(Predicted)
form :solid
color :white to off-white
Water Solubility :Soluble in water at 10mg/ml
Sensitive :Light Sensitive
Safety Information
Symbol(GHS): | ||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Signal word: | Danger | |||||||||||||||||||||
Hazard statements: |
|
|||||||||||||||||||||
Precautionary statements: |
|
Description
Mutations in the p53 tumor suppressor are found in many different neoplastic cells. PRIMA-1 restores sequence-specific DNA binding and transactivational activity to mutant p53 proteins at relatively high μM to mM concentrations. It is therefore a unique anti-oncogenic substance, working as a re-activator of the apoptotic function of mutant p53 via conformational modulation of function-specific epitopes. PRIMA-1 represents a novel lead compound which may be further modified to provide more potent therapeutic agents acting via the reactivation mechanism.More related product prices
JX401 1670-87-7 CYCLIC-PIFITHRIN-ALPHA SB 202190 SB 239063 CP 31398 FHPI HCL PD 169316 Pifithrin-α (PFTα)Related product price
- JX401
$45-1274 - 1670-87-7
$37-2148.3 - CYCLIC-PIFITHRIN-ALPHA
$53-607
Suppliers and manufacturers
ATK CHEMICAL COMPANY LIMITED
Zhejiang J&C Biological Technology Co.,Limited
InvivoChem
TargetMol Chemicals Inc.
Shanghai Acmec Biochemical Technology Co., Ltd.
Aladdin Scientific
Wuhan Jingkang en Biomedical Technology Co., Ltd
SHANGHAI KEAN TECHNOLOGY CO., LTD.
Shanghai Boyle Chemical Co., Ltd.