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ChemicalBook >> CAS DataBase List >> PRIMA-1

PRIMA-1

PRIMA-1 price.
  • $19 - $2325
  • Product name: PRIMA-1
  • CAS: 5608-24-2
  • MF: C9H15NO3
  • MW: 185.22
  • EINECS:
  • MDL Number:MFCD19199989
  • Synonyms:PRIMA-1;P53 REACTIVATION AND INDUCTION OF MASSIVE APOPTOSIS;2,2-BIS(HYDROXYMETHYL)-1-AZABICYCLO[2,2,2]OCTAN-3-ONE;2,2-BIS(HYDROXYMETHYL)-3-QUINUCLIDINONE;2,2-dimethylolquinuclidin-3-one;7,7-bis(hydroxymethyl)-1-azabicyclo[2.2.2]octan-8-one;PRIMA-1 - CAS 5608-24-2 - Calbiochem;2-Bis(hydroxymethyl)-3-quinuclidinone
34 prices
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Brand
  • AHH
  • AK Scientific
  • Alfa Aesar
  • Ambeed
  • ApexBio Technology
  • Arctom
  • Cayman Chemical
  • Crysdot
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  • DC Chemicals
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
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  • 1unit
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 50
  • 1g
  • 10mM(in 1mL DMSO)
  • ManufacturerAHH
  • Product numberAPI-1964
  • Product descriptionPRIMA-1 Prima-1
  • Packaging1g
  • Price$1200
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number1997AH
  • Product description2,2-Bis(hydroxymethyl)-3-quinuclidinone
  • Packaging5mg
  • Price$124
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ64071
  • Product descriptionPRIMA-1
  • Packaging10mg
  • Price$219.65
  • Updated2024-03-01
  • Buy
  • ManufacturerAmbeed
  • Product numberA755385
  • Product descriptionPRIMA-1 98%
  • Packaging5mg
  • Price$51
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA755385
  • Product descriptionPRIMA-1 98%
  • Packaging10mg
  • Price$77
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA755385
  • Product descriptionPRIMA-1 98%
  • Packaging25mg
  • Price$134
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA755385
  • Product descriptionPRIMA-1 98%
  • Packaging50mg
  • Price$173
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA755385
  • Product descriptionPRIMA-1 98%
  • Packaging100mg
  • Price$224
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA755385
  • Product descriptionPRIMA-1 98%
  • Packaging1g
  • Price$2325
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4483
  • Product descriptionPRIMA-1
  • Packaging1unit
  • Price$28
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4483
  • Product descriptionPRIMA-1
  • Packaging10mM(in 1mL DMSO)
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4483
  • Product descriptionPRIMA-1
  • Packaging5mg
  • Price$56
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4483
  • Product descriptionPRIMA-1
  • Packaging10mg
  • Price$75
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4483
  • Product descriptionPRIMA-1
  • Packaging50mg
  • Price$245
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS658179
  • Product descriptionPRIMA-1 98%
  • Packaging5mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number63520
  • Product descriptionPRIMA-1 ≥95%
  • Packaging1mg
  • Price$19
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AHH API-1964 PRIMA-1 Prima-1 1g $1200 2021-12-16 Buy
AK Scientific 1997AH 2,2-Bis(hydroxymethyl)-3-quinuclidinone 5mg $124 2021-12-16 Buy
Alfa Aesar J64071 PRIMA-1 10mg $219.65 2024-03-01 Buy
Ambeed A755385 PRIMA-1 98% 5mg $51 2021-12-16 Buy
Ambeed A755385 PRIMA-1 98% 10mg $77 2021-12-16 Buy
Ambeed A755385 PRIMA-1 98% 25mg $134 2021-12-16 Buy
Ambeed A755385 PRIMA-1 98% 50mg $173 2021-12-16 Buy
Ambeed A755385 PRIMA-1 98% 100mg $224 2021-12-16 Buy
Ambeed A755385 PRIMA-1 98% 1g $2325 2021-12-16 Buy
ApexBio Technology A4483 PRIMA-1 1unit $28 2021-12-16 Buy
ApexBio Technology A4483 PRIMA-1 10mM(in 1mL DMSO) $50 2021-12-16 Buy
ApexBio Technology A4483 PRIMA-1 5mg $56 2021-12-16 Buy
ApexBio Technology A4483 PRIMA-1 10mg $75 2021-12-16 Buy
ApexBio Technology A4483 PRIMA-1 50mg $245 2021-12-16 Buy
Arctom AS658179 PRIMA-1 98% 5mg $50 2021-12-16 Buy
Cayman Chemical 63520 PRIMA-1 ≥95% 1mg $19 2024-03-01 Buy

Properties

Melting point :146-147 °C
Boiling point :353.7±17.0 °C(Predicted)
Density :1.32±0.1 g/cm3(Predicted)
storage temp. :Inert atmosphere,2-8°C
solubility :H2O: >10mg/mL
pka :13.68±0.10(Predicted)
form :solid
color :white to off-white
Water Solubility :Soluble in water at 10mg/ml
Sensitive :Light Sensitive

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled Sensitisation, respiratory Category 1 Danger GHS hazard pictograms P261, P285, P304+P341, P342+P311,P501
Precautionary statements:

Description

Mutations in the p53 tumor suppressor are found in many different neoplastic cells. PRIMA-1 restores sequence-specific DNA binding and transactivational activity to mutant p53 proteins at relatively high μM to mM concentrations. It is therefore a unique anti-oncogenic substance, working as a re-activator of the apoptotic function of mutant p53 via conformational modulation of function-specific epitopes. PRIMA-1 represents a novel lead compound which may be further modified to provide more potent therapeutic agents acting via the reactivation mechanism.

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