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ChemicalBook >> CAS DataBase List >> SANT-1

SANT-1

SANT-1 price.
  • $55 - $1593.9
  • Product name: SANT-1
  • CAS: 304909-07-7
  • MF: C23H27N5
  • MW: 373.49
  • EINECS:
  • MDL Number:MFCD01827306
  • Synonyms:N-[(3,5-DIMETHYL-1-PHENYL-1H-PYRAZOL-4-YL)METHYLENE]-4-(PHENYLMETHYL)-1-PIPERAZINAMINE;SANT-1;(4-Benzyl-piperazin-1-yl)-(3,5-dimethyl-1-phenyl-1H-pyrazol-4-ylmethylene)-amine;1-Piperazinamine, N-[(3,5-dimethyl-1-phenyl-1H-pyrazol-4-yl)methylene]-4-(phenylmethyl)-;(E)-N-(4-benzylpiperazin-1-yl)-1-(3,5-dimethyl-1-phenylpyrazol-4-yl)methanimine;SANT1 10MG;SANT1;SANT 1;SANT-1 - CAS 304909-07-7 - Calbiochem
20 prices
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  • AK Scientific
  • Alfa Aesar
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
  • Sigma-Aldrich
Package
  • 1MG
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 250mg
  • 1g
  • 100MG
  • 10mM(in 1mL DMSO)
  • ManufacturerAK Scientific
  • Product number2700AH
  • Product descriptionSANT-1
  • Packaging10mg
  • Price$196
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ65294
  • Product descriptionSANT-1
  • Packaging10mg
  • Price$169
  • Updated2023-06-20
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0000824
  • Product descriptionSANT-1 95.00%
  • Packaging100MG
  • Price$1593.9
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0000824
  • Product descriptionSANT-1 95.00%
  • Packaging10MG
  • Price$704.55
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0000824
  • Product descriptionSANT-1 95.00%
  • Packaging1MG
  • Price$165.9
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8659
  • Product descriptionSANT-1
  • Packaging10mM(in 1mL DMSO)
  • Price$80
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8659
  • Product descriptionSANT-1
  • Packaging10mg
  • Price$103
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8659
  • Product descriptionSANT-1
  • Packaging50mg
  • Price$399
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number14933
  • Product descriptionSANT 1 ≥98%
  • Packaging1mg
  • Price$62
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number14933
  • Product descriptionSANT 1 ≥98%
  • Packaging5mg
  • Price$107
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number14933
  • Product descriptionSANT 1 ≥98%
  • Packaging10mg
  • Price$168
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0018354
  • Product descriptionSANT-1 99.85%
  • Packaging5mg
  • Price$55
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0018354
  • Product descriptionSANT-1 99.85%
  • Packaging10mg
  • Price$90
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0018354
  • Product descriptionSANT-1 99.85%
  • Packaging50mg
  • Price$250
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0018354
  • Product descriptionSANT-1 99.85%
  • Packaging100mg
  • Price$450
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC8327
  • Product descriptionSANT-1 >98%
  • Packaging250mg
  • Price$750
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 2700AH SANT-1 10mg $196 2021-12-16 Buy
Alfa Aesar J65294 SANT-1 10mg $169 2023-06-20 Buy
American Custom Chemicals Corporation API0000824 SANT-1 95.00% 100MG $1593.9 2021-12-16 Buy
American Custom Chemicals Corporation API0000824 SANT-1 95.00% 10MG $704.55 2021-12-16 Buy
American Custom Chemicals Corporation API0000824 SANT-1 95.00% 1MG $165.9 2021-12-16 Buy
ApexBio Technology A8659 SANT-1 10mM(in 1mL DMSO) $80 2021-12-16 Buy
ApexBio Technology A8659 SANT-1 10mg $103 2021-12-16 Buy
ApexBio Technology A8659 SANT-1 50mg $399 2021-12-16 Buy
Cayman Chemical 14933 SANT 1 ≥98% 1mg $62 2024-03-01 Buy
Cayman Chemical 14933 SANT 1 ≥98% 5mg $107 2024-03-01 Buy
Cayman Chemical 14933 SANT 1 ≥98% 10mg $168 2024-03-01 Buy
ChemScene CS-0018354 SANT-1 99.85% 5mg $55 2021-12-16 Buy
ChemScene CS-0018354 SANT-1 99.85% 10mg $90 2021-12-16 Buy
ChemScene CS-0018354 SANT-1 99.85% 50mg $250 2021-12-16 Buy
ChemScene CS-0018354 SANT-1 99.85% 100mg $450 2021-12-16 Buy
DC Chemicals DC8327 SANT-1 >98% 250mg $750 2021-12-16 Buy

Properties

Melting point :104-106°C
Boiling point :547.4±50.0 °C(Predicted)
Density :1.13±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in DMSO with warming
form :White solid
pka :7.35±0.10(Predicted)
color :White to off-white
Sensitive :Moisture & Light Sensitive
CAS DataBase Reference :304909-07-7

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Smoothened (SMO) is a GPCR-like receptor which, with Patched, mediates hedgehog signaling to regulate gene expression through the Gli transcription factors. SANT 1 is a potent inhibitor of hedgehog signaling that acts by directly antagonizing SMO (IC50 = 20 nM). It counteracts SMO activation by the SMO agonist SAG but only partially competes with SAG binding to SMO. SANT 1 targets inactive SMO while it is in the cytoplasm, before it relocates to the primary cilium and is activated. Through antagonism of SMO, SANT 1 represses Gli-mediated transcription in a variety of cell types.

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