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ChemicalBook >> CAS DataBase List >> ROTTLERIN

ROTTLERIN

ROTTLERIN price.
  • $45 - $565
  • Product name: ROTTLERIN
  • CAS: 82-08-6
  • MF: C30H28O8
  • MW: 516.54
  • EINECS:201-395-4
  • MDL Number:MFCD00017361
  • Synonyms:3'-[(8-CINNAMOYL-5,7-DIHYDROXY-2,2-DIMETHYL-2H-1-BENZOPYRAN-6-YL)METHYL]-2',4',6'-TRIHYDROXY-5'-METHYLACETOPHENONE;4’,6’-trihydroxy-5’-methyl-methyl)-2 ;acetophenone,3’-((8-cinnamoyl-5,7-dihydroxy-2,2-dimethyl-2h-1-benzopyran-6-yl) ;2-Propen-1-one, 1-[6-[(3-acetyl-2,4,6-trihydroxy-5-methylphenyl)methyl]-5,7-dihydroxy-2,2-dimethyl-2H-1-benzopyran-8-yl]-3-phenyl-, (2E)-;1-[6-[(3-acetyl-2,4,6-trihydroxy-5-methylphenyl)methyl]-5,7-dihydroxy-2,2-dimethyl-2h-1-benzopyran-8-yl]-3-phenyl-2-propen-1-one;(E)-1-[6-[(3-acetyl-2,4,6-trihydroxy-5-methylphenyl)methyl]-5,7-dihydroxy-2,2-dimethyl-2H-1-benzopyran-8-yl]-3-phenyl-2-propen-1-one;Rottlerin,98%;Rottlerin, 98% 10MG
19 prices
Selected condition：
Brand
  • Adipogen Life Sciences
  • AHH
  • ApexBio Technology
  • Arctom
  • Biosynth Carbosynth
  • Cayman Chemical
  • ChemScene
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 10
  • 25mg
  • 10mg
  • 50
  • 50mg
  • 100mg
  • 0.1g
  • 250mg
  • 500mg
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CN2-0526-M010
  • Product descriptionRottlerin ≥98%(HPLC)
  • Packaging10mg
  • Price$45
  • Updated2021-12-16
  • Buy
  • ManufacturerAHH
  • Product numberMT-58471
  • Product descriptionRottlerin 98%
  • Packaging0.1g
  • Price$370
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6803
  • Product descriptionRottlerin
  • Packaging10mg
  • Price$68
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS601734
  • Product descriptionRottlerin 97%
  • Packaging100mg
  • Price$175
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS601734
  • Product descriptionRottlerin 97%
  • Packaging250mg
  • Price$345
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFR29637
  • Product descriptionRottlerin
  • Packaging25mg
  • Price$72.5
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFR29637
  • Product descriptionRottlerin
  • Packaging50mg
  • Price$115
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFR29637
  • Product descriptionRottlerin
  • Packaging100mg
  • Price$180
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFR29637
  • Product descriptionRottlerin
  • Packaging250mg
  • Price$355
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFR29637
  • Product descriptionRottlerin
  • Packaging500mg
  • Price$565
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number12006
  • Product descriptionRottlerin ≥90%
  • Packaging10mg
  • Price$62
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number12006
  • Product descriptionRottlerin ≥90%
  • Packaging50mg
  • Price$239
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0014823
  • Product descriptionRottlerin 97.03%
  • Packaging10mg
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0014823
  • Product descriptionRottlerin 97.03%
  • Packaging25mg
  • Price$130
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number557370
  • Product descriptionRottlerin - CAS 82-08-6 - Calbiochem
  • Packaging10mg
  • Price$144
  • Updated2024-03-01
  • Buy
  • ManufacturerTocris
  • Product number1610
  • Product descriptionRottlerin ≥95%(HPLC)
  • Packaging10
  • Price$95
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences AG-CN2-0526-M010 Rottlerin ≥98%(HPLC) 10mg $45 2021-12-16 Buy
AHH MT-58471 Rottlerin 98% 0.1g $370 2021-12-16 Buy
ApexBio Technology B6803 Rottlerin 10mg $68 2021-12-16 Buy
Arctom AS601734 Rottlerin 97% 100mg $175 2021-12-16 Buy
Arctom AS601734 Rottlerin 97% 250mg $345 2021-12-16 Buy
Biosynth Carbosynth FR29637 Rottlerin 25mg $72.5 2021-12-16 Buy
Biosynth Carbosynth FR29637 Rottlerin 50mg $115 2021-12-16 Buy
Biosynth Carbosynth FR29637 Rottlerin 100mg $180 2021-12-16 Buy
Biosynth Carbosynth FR29637 Rottlerin 250mg $355 2021-12-16 Buy
Biosynth Carbosynth FR29637 Rottlerin 500mg $565 2021-12-16 Buy
Cayman Chemical 12006 Rottlerin ≥90% 10mg $62 2024-03-01 Buy
Cayman Chemical 12006 Rottlerin ≥90% 50mg $239 2024-03-01 Buy
ChemScene CS-0014823 Rottlerin 97.03% 10mg $60 2021-12-16 Buy
ChemScene CS-0014823 Rottlerin 97.03% 25mg $130 2021-12-16 Buy
Sigma-Aldrich 557370 Rottlerin - CAS 82-08-6 - Calbiochem 10mg $144 2024-03-01 Buy
Tocris 1610 Rottlerin ≥95%(HPLC) 10 $95 2021-12-16 Buy

Properties

Melting point :200 °C
Boiling point :521.39°C (rough estimate)
Density :1.2051 (rough estimate)
refractive index :1.4900 (estimate)
storage temp. :2-8°C
solubility :Soluble in DMSO (up to 50 mg/ml).
form :Powder
pka :6.92±0.40(Predicted)
color :Orange to brown
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
LogP :8.660 (est)
CAS DataBase Reference :82-08-6(CAS DataBase Reference)

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Rottlerin was originally identified as an inhibitor of PKCδ (IC50 = 3 μM), but can also inhibit CAM kinase III and a wide range of protein kinases, including PRAK and MAPKAP-K2 (IC50s = 1.9 and 5 μM, respectively). It can act as a direct mitochondrial uncoupler, and stimulates autophagy by targeting a signaling cascade upstream of mTORC1. Rottlerin has also been shown to have neuroprotective effects in an MPTP animal model of Parkinson’s disease.

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