OTAVA-BB 7070707015
- $16 - $1700
- Product name: OTAVA-BB 7070707015
- CAS: 934593-90-5
- MF: C26H29NO5
- MW: 435.51
- EINECS:
- MDL Number:MFCD09907563
- Synonyms:OTAVA-BB 7070707015;CAY10585;HIF-1α inhibitor;LW6;LW8;4-Hydroxy-3-[[2-(4-tricyclo[3.3.1.13,7]dec-1-ylphenoxy)acetyl]aMino]-benzoic Acid Methyl Ester;Hypoxia inducible factor-1α inhibitor;CAY 10585;CAY-10585;CAY10585;LW6
28 prices
Selected condition:
Brand
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- Axon Medchem
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Tocris
- TRC
Package
- 10
- 1MG
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- ManufacturerAK Scientific
- Product number1793AH
- Product descriptionHypoxiainduciblefactor-1Ainhibitor
- Packaging5mg
- Price$167
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA121335
- Product descriptionLW6 97%
- Packaging5mg
- Price$39
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA121335
- Product descriptionLW6 97%
- Packaging10mg
- Price$63
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA121335
- Product descriptionLW6 97%
- Packaging25mg
- Price$147
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA121335
- Product descriptionLW6 97%
- Packaging50mg
- Price$255
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA121335
- Product descriptionLW6 97%
- Packaging100mg
- Price$331
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0001046
- Product description4-HYDROXY-3-((2-(4-TRICYCLO(3.3.1.13,7)DEC-1-YLPHENOXY)ACETYL)AMINO)-BENZOIC ACID, METHYL ESTER 95.00%
- Packaging1MG
- Price$132.3
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0001046
- Product description4-HYDROXY-3-((2-(4-TRICYCLO(3.3.1.13,7)DEC-1-YLPHENOXY)ACETYL)AMINO)-BENZOIC ACID, METHYL ESTER 95.00%
- Packaging5MG
- Price$505.62
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon2480
- Product descriptionLW6 99%
- Packaging10mg
- Price$93.5
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number10012682
- Product descriptionCAY10585 ≥97%
- Packaging1mg
- Price$16
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10012682
- Product descriptionCAY10585 ≥97%
- Packaging5mg
- Price$63
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10012682
- Product descriptionCAY10585 ≥97%
- Packaging10mg
- Price$109
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10012682
- Product descriptionCAY10585 ≥97%
- Packaging25mg
- Price$235
- Updated2024-03-01
- Buy
- ManufacturerChemenu
- Product numberCM255871
- Product descriptionMethyl3-(2-(4-(adamantan-1-yl)phenoxy)acetamido)-4-hydroxybenzoate 97%
- Packaging100mg
- Price$566
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-6439
- Product descriptionLW6 98.16%
- Packaging5mg
- Price$72
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-6439
- Product descriptionLW6 98.16%
- Packaging10mg
- Price$108
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | 1793AH | Hypoxiainduciblefactor-1Ainhibitor | 5mg | $167 | 2021-12-16 | Buy |
Ambeed | A121335 | LW6 97% | 5mg | $39 | 2021-12-16 | Buy |
Ambeed | A121335 | LW6 97% | 10mg | $63 | 2021-12-16 | Buy |
Ambeed | A121335 | LW6 97% | 25mg | $147 | 2021-12-16 | Buy |
Ambeed | A121335 | LW6 97% | 50mg | $255 | 2021-12-16 | Buy |
Ambeed | A121335 | LW6 97% | 100mg | $331 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | KIN0001046 | 4-HYDROXY-3-((2-(4-TRICYCLO(3.3.1.13,7)DEC-1-YLPHENOXY)ACETYL)AMINO)-BENZOIC ACID, METHYL ESTER 95.00% | 1MG | $132.3 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | KIN0001046 | 4-HYDROXY-3-((2-(4-TRICYCLO(3.3.1.13,7)DEC-1-YLPHENOXY)ACETYL)AMINO)-BENZOIC ACID, METHYL ESTER 95.00% | 5MG | $505.62 | 2021-12-16 | Buy |
Axon Medchem | Axon2480 | LW6 99% | 10mg | $93.5 | 2021-12-16 | Buy |
Cayman Chemical | 10012682 | CAY10585 ≥97% | 1mg | $16 | 2024-03-01 | Buy |
Cayman Chemical | 10012682 | CAY10585 ≥97% | 5mg | $63 | 2024-03-01 | Buy |
Cayman Chemical | 10012682 | CAY10585 ≥97% | 10mg | $109 | 2024-03-01 | Buy |
Cayman Chemical | 10012682 | CAY10585 ≥97% | 25mg | $235 | 2024-03-01 | Buy |
Chemenu | CM255871 | Methyl3-(2-(4-(adamantan-1-yl)phenoxy)acetamido)-4-hydroxybenzoate 97% | 100mg | $566 | 2021-12-16 | Buy |
ChemScene | CS-6439 | LW6 98.16% | 5mg | $72 | 2021-12-16 | Buy |
ChemScene | CS-6439 | LW6 98.16% | 10mg | $108 | 2021-12-16 | Buy |
Properties
Boiling point :647.4±55.0 °C(Predicted)
Density :1.295±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO:17.5(Max Conc. mg/mL);40.18(Max Conc. mM)
DMF:25.6(Max Conc. mg/mL);58.8(Max Conc. mM) pka :7.59±0.48(Predicted)
form :powder to crystal
color :White to Light yellow to Light orange
Density :1.295±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO:17.5(Max Conc. mg/mL);40.18(Max Conc. mM)
DMF:25.6(Max Conc. mg/mL);58.8(Max Conc. mM) pka :7.59±0.48(Predicted)
form :powder to crystal
color :White to Light yellow to Light orange
Safety Information
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Description
Hypoxia Inducible Factor-1α Inhibitor is a novel small molecule which inhibits HIF by reducing HIF-1α accumulation and gene transcriptional activity. In a gene reporter assay using human AGS and Hep3B cell lines, hypoxia inducible factor-1α Inhibitor prevented HIF-1 transcriptional activity with IC50 values of 2.6 and 0.7 μM, respectively. Hypoxia inducible factor-1α inhibitor blocks HIF-1α accumulation in Hep3B cells in a concentration and time-dependent manner, with complete inhibition at a concentration of 30 μM within 12 hours. Hypoxia inducible factor-1α inhibitor also significantly suppresses transcription of the HIF-1 target genes VEGF and erythropoietin at 10 μM.More related product prices
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