ON-01910
- $34 - $2000
- Product name: ON-01910
- CAS: 1225497-78-8
- MF: C21H26NNaO8S
- MW: 475.49
- EINECS:-0
- MDL Number:MFCD11655911
- Synonyms:ON-01910;Estybon;N-[2-Methoxy-5-[[[2-(2,4,6-trimethoxyphenyl)ethenyl]sulfonyl]methyl]phenyl]glycine sodium salt;ON 01910 sodium salt;ON-01910;ESTYBON;Rigosertib (ON-01910);N-[2-methoxy-5-[[[2-(2,4,6-trimethoxyphenyl)ethenyl]sulfonyl]methyl]phenyl]-glycine,sodium salt (1:1);N-[2-Methoxy-5-[[[2-(2,4,6-trimethoxyphenyl)ethenyl]sulfonyl]methyl]phenyl]glycine sodium salt Rigosertib (ON-01910)
15 prices
Selected condition:
Brand
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Cayman Chemical
- Chemenu
- Crysdot
- DC Chemicals
- TRC
Package
- 1mg
- 5MG
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- 10mM(in 1mL DMSO)
- ManufacturerAK Scientific
- Product numberX7376
- Product descriptionSodium{[2-methoxy-5-({[(E)-2-(2,4,6-trimethoxyphenyl)vinyl]sulfonyl}methyl)phenyl]amino}acetate
- Packaging25mg
- Price$420
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000600
- Product descriptionON-01910 95.00%
- Packaging5MG
- Price$330
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA1404
- Product descriptionRigosertibsodiumsalt
- Packaging10mM(in 1mL DMSO)
- Price$220
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN60271
- Product descriptionRigosertib(ON-01910) ≥98%
- Packaging10mg
- Price$238
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number15553
- Product descriptionON-01910 (sodium salt) ≥98%
- Packaging1mg
- Price$34
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number15553
- Product descriptionON-01910 (sodium salt) ≥98%
- Packaging5mg
- Price$85
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number15553
- Product descriptionON-01910 (sodium salt) ≥98%
- Packaging10mg
- Price$150
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number15553
- Product descriptionON-01910 (sodium salt) ≥98%
- Packaging25mg
- Price$330
- Updated2024-03-01
- Buy
- ManufacturerChemenu
- Product numberCM295047
- Product descriptionSodium2-((2-methoxy-5-(((2,4,6-trimethoxystyryl)sulfonyl)methyl)phenyl)amino)acetate 95%
- Packaging50mg
- Price$409
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31004210
- Product descriptionON-01910.Na 95+%
- Packaging25mg
- Price$242
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31004210
- Product descriptionON-01910.Na 95+%
- Packaging50mg
- Price$411
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC7265
- Product descriptionRigosertib >98%
- Packaging100mg
- Price$500
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC7265
- Product descriptionRigosertib >98%
- Packaging250mg
- Price$1000
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC7265
- Product descriptionRigosertib >98%
- Packaging1g
- Price$2000
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberO657000
- Product descriptionON-01910SodiumSalt
- Packaging25mg
- Price$250
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | X7376 | Sodium{[2-methoxy-5-({[(E)-2-(2,4,6-trimethoxyphenyl)vinyl]sulfonyl}methyl)phenyl]amino}acetate | 25mg | $420 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | KIN0000600 | ON-01910 95.00% | 5MG | $330 | 2021-12-16 | Buy |
ApexBio Technology | A1404 | Rigosertibsodiumsalt | 10mM(in 1mL DMSO) | $220 | 2021-12-16 | Buy |
Arctom | CFN60271 | Rigosertib(ON-01910) ≥98% | 10mg | $238 | 2021-12-16 | Buy |
Cayman Chemical | 15553 | ON-01910 (sodium salt) ≥98% | 1mg | $34 | 2024-03-01 | Buy |
Cayman Chemical | 15553 | ON-01910 (sodium salt) ≥98% | 5mg | $85 | 2024-03-01 | Buy |
Cayman Chemical | 15553 | ON-01910 (sodium salt) ≥98% | 10mg | $150 | 2024-03-01 | Buy |
Cayman Chemical | 15553 | ON-01910 (sodium salt) ≥98% | 25mg | $330 | 2024-03-01 | Buy |
Chemenu | CM295047 | Sodium2-((2-methoxy-5-(((2,4,6-trimethoxystyryl)sulfonyl)methyl)phenyl)amino)acetate 95% | 50mg | $409 | 2021-12-16 | Buy |
Crysdot | CD31004210 | ON-01910.Na 95+% | 25mg | $242 | 2021-12-16 | Buy |
Crysdot | CD31004210 | ON-01910.Na 95+% | 50mg | $411 | 2021-12-16 | Buy |
DC Chemicals | DC7265 | Rigosertib >98% | 100mg | $500 | 2021-12-16 | Buy |
DC Chemicals | DC7265 | Rigosertib >98% | 250mg | $1000 | 2021-12-16 | Buy |
DC Chemicals | DC7265 | Rigosertib >98% | 1g | $2000 | 2021-12-16 | Buy |
TRC | O657000 | ON-01910SodiumSalt | 25mg | $250 | 2021-12-16 | Buy |
Properties
Melting point :>256oC (dec.)
storage temp. :Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility :Methanol (Slightly), Water (Slightly)
form :Solid
color :Pale Yellow to Pale Green
storage temp. :Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility :Methanol (Slightly), Water (Slightly)
form :Solid
color :Pale Yellow to Pale Green
Safety Information
Symbol(GHS): | ||||||||
---|---|---|---|---|---|---|---|---|
Signal word: | ||||||||
Hazard statements: |
|
|||||||
Precautionary statements: |
|
Description
ON-01910 is a potent, non-ATP-competitive inhibitor of polo-like kinase 1 (Plk1; IC50 = 9 nM), a serine/threonine protein kinase involved in the regulation of cell cycling. It induces apoptosis in a wide array of tumor cell lines (GI50 = 50-200 nM) and blocks the growth of multidrug resistant cancer cell lines. ON-01910 is active in vivo when administered intraperitoneally and synergizes with chemotherapeutic agents, preventing tumor growth or abolishing tumors in human xenograft nude mouse models.Related product price
- Volasertib (BI 6727)
$24-2245.7 - BI 2536
$37-2839 - MG-132
$11-1000