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ChemicalBook >> CAS DataBase List >> OKADAIC ACID

OKADAIC ACID

OKADAIC ACID price.
  • $57 - $1960
  • Product name: OKADAIC ACID
  • CAS: 78111-17-8
  • MF: C44H68O13
  • MW: 805
  • EINECS:616-589-8
  • MDL Number:MFCD00083455
  • Synonyms:1,7-Dioxaspiro[5.5]undec-10-ene-2-propanoicacid, a,5-dihydroxy-a,10-dimethyl-8-[(1R,2E)-1-methyl-3-[(2R,4'aR,5R,6'S,8'R,8'aS)-octahydro-8'-hydroxy-6'-[(1S,3S)-1-hydroxy-3-[(2S,3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undec-2-yl]butyl]-7'-methylenespiro[furan-2(;Okadaic acid 35-Demethyl-DTX 1 NSC 677083 35-Demethyldinophysistoxin 1;OA;OKADAIC ACID, PROROCENTRUM CONCAVUM;35-Demethyldinophysistoxin 1;35-Demethyl-DTX 1;NSC 677083;9,10-DEEPITHIO-9,10-DIDEHYDROACANTHIFOLICIN
27 prices
Selected condition:
Brand
  • Adipogen Life Sciences
  • Alfa Aesar
  • ApexBio Technology
  • Biorbyt Ltd
  • Cayman Chemical
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 20μg
  • 25μg
  • 25ug
  • 50μg
  • 50ug
  • 100μg
  • 100ug
  • 0.1mg
  • 300μg
  • 500μg
  • 0.5mg
  • 500ug
  • 1mg
  • 25U
  • 50microgram
  • 50ug(solution)
  • 100ug(solution)
  • 100microg
  • 300microg
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CN2-0056-C100
  • Product descriptionOkadaicacid(freeacid)(highpurity) ≥98%(HPLC)
  • Packaging100μg
  • Price$185
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ60155
  • Product descriptionOkadaic acid, 98%
  • Packaging50microgram
  • Price$121
  • Updated2023-06-20
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ60155
  • Product descriptionOkadaic acid, 98%
  • Packaging100microg
  • Price$213
  • Updated2023-06-20
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ60155
  • Product descriptionOkadaic acid, 98%
  • Packaging300microg
  • Price$627
  • Updated2023-06-20
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4540
  • Product descriptionOkadaic acid
  • Packaging50ug(solution)
  • Price$103
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4540
  • Product descriptionOkadaic acid
  • Packaging100ug(solution)
  • Price$194
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb545972
  • Product descriptionOkadaic acid >98%
  • Packaging20μg
  • Price$127.5
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb545972
  • Product descriptionOkadaic acid >98%
  • Packaging100μg
  • Price$290.7
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb61066
  • Product descriptionOkadaic Acid, Free Acid >98% pure
  • Packaging50μg
  • Price$329.8
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb61066
  • Product descriptionOkadaic Acid, Free Acid >98% pure
  • Packaging100μg
  • Price$368.9
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb61066
  • Product descriptionOkadaic Acid, Free Acid >98% pure
  • Packaging300μg
  • Price$595
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb61066
  • Product descriptionOkadaic Acid, Free Acid >98% pure
  • Packaging1mg
  • Price$1395.7
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number10011490
  • Product descriptionOkadaic Acid ≥95%
  • Packaging25μg
  • Price$57
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10011490
  • Product descriptionOkadaic Acid ≥95%
  • Packaging50μg
  • Price$100
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10011490
  • Product descriptionOkadaic Acid ≥95%
  • Packaging100μg
  • Price$166
  • Updated2024-03-01
  • Buy
  • ManufacturerMedical Isotopes, Inc.
  • Product number66529
  • Product descriptionOkadaic acid
  • Packaging0.5mg
  • Price$1150
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences AG-CN2-0056-C100 Okadaicacid(freeacid)(highpurity) ≥98%(HPLC) 100μg $185 2021-12-16 Buy
Alfa Aesar J60155 Okadaic acid, 98% 50microgram $121 2023-06-20 Buy
Alfa Aesar J60155 Okadaic acid, 98% 100microg $213 2023-06-20 Buy
Alfa Aesar J60155 Okadaic acid, 98% 300microg $627 2023-06-20 Buy
ApexBio Technology A4540 Okadaic acid 50ug(solution) $103 2021-12-16 Buy
ApexBio Technology A4540 Okadaic acid 100ug(solution) $194 2021-12-16 Buy
Biorbyt Ltd orb545972 Okadaic acid >98% 20μg $127.5 2021-12-16 Buy
Biorbyt Ltd orb545972 Okadaic acid >98% 100μg $290.7 2021-12-16 Buy
Biorbyt Ltd orb61066 Okadaic Acid, Free Acid >98% pure 50μg $329.8 2021-12-16 Buy
Biorbyt Ltd orb61066 Okadaic Acid, Free Acid >98% pure 100μg $368.9 2021-12-16 Buy
Biorbyt Ltd orb61066 Okadaic Acid, Free Acid >98% pure 300μg $595 2021-12-16 Buy
Biorbyt Ltd orb61066 Okadaic Acid, Free Acid >98% pure 1mg $1395.7 2021-12-16 Buy
Cayman Chemical 10011490 Okadaic Acid ≥95% 25μg $57 2024-03-01 Buy
Cayman Chemical 10011490 Okadaic Acid ≥95% 50μg $100 2024-03-01 Buy
Cayman Chemical 10011490 Okadaic Acid ≥95% 100μg $166 2024-03-01 Buy
Medical Isotopes, Inc. 66529 Okadaic acid 0.5mg $1150 2021-12-16 Buy

Properties

Melting point :164-166 °C
alpha :D20 +21° (c = 0.33 in CHCl3); D25 +25.4° (c = 0.24 in CHCl3)
Boiling point :672.95°C (rough estimate)
Density :1.0795 (rough estimate)
refractive index :1.5940 (estimate)
storage temp. :-20°C
solubility :DMSO: ≥1 mg/mL
form :translucent film
pka :3.87±0.16(Predicted)
color :translucent
optical activity :+2120 (CHCl3)
Water Solubility :It is soluble in ethanol (25 mg/ml), DMSO (25 mg/ml), methanol (<1 mg/ml), chloroform, acetone, ethyl acetate, DMF, and dimethylsulfoxide. Insoluble in water, unless first dissolved in organic solvents, such as DMSO or ethanol.
Merck :13,6891
Stability :Stable. Light and heat-sensitive. Combustible. Incompatible with strong oxidizing agents.
CAS DataBase Reference :78111-17-8
EPA Substance Registry System :1,7-Dioxaspiro[5.5]undec-10-ene-2-propanoic acid, .alpha,5-dihydroxy-.alpha.,10-dimethyl-8-[(1R,2E)-1-methyl-3-[(2R,4'aR,5R,6'S,8'R,8'aS)-octahydro-8'-hydroxy-6'-[(1S,3S)-1-hydroxy-3-[(2S,3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undec-2-yl]butyl]-7'-methylenespiro[furan-2(3H),2'(3'H)-pyrano[3,2-b]pyran]-5-yl]-2-propen-1-yl]-, (.alpha.R,2S,5R,6R,8S)- (78111-17-8)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Description

Okadaic acid, is used as an activator of PKC and inhibitor of PP1 and PP2A phosphatases. The hydrophobic backbone of okadaic acid enables it to enter cells where it stimulates intracellular protein phosphorylation. It mimics the effects of insulin, enhances transmitter release at neuromuscular junctions, causes vasodilation and is a very potent tumor promoter. Okadaic acid is an extremely useful tool for studying cellular processes that are regulated by phosphorylation. It is shown to activate atypical protein kinase C in adipocytes.

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